UniProt Accession

 F6YA11_MOUSE; F6YA11 

Genbank Protein ID

 AL772359 

Genbank Nucleotide ID

  

Protein Name

 Exportin-1 

Protein Synonyms/Alias

  

Gene Name

 Xpo1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
38	LLGLCEQKRGKDNKA	ubiquitination	[1]
70	RAHWKFLKTVVNKLF	acetylation	[2]
148	LKDPETVKQLGSILK	acetylation	[3]
155	KQLGSILKTNVRACK	ubiquitination	[1]
162	KTNVRACKAVGHPFV	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [3] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 233 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IDA:MGI.
 GO:0030529; C:ribonucleoprotein complex; ISO:MGI.
 GO:0008565; F:protein transporter activity; IDA:MGI.
 GO:0006611; P:protein export from nucleus; IDA:MGI.
 GO:0034504; P:protein localization to nucleus; IMP:MGI.
 GO:0010824; P:regulation of centrosome duplication; IMP:MGI.
 GO:0042176; P:regulation of protein catabolic process; IMP:MGI.
 GO:0046825; P:regulation of protein export from nucleus; IMP:MGI. 

Interpro

 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR014877; CRM1_C_dom. 

Pfam

 PF08767; CRM1_C 

SMART

  

PROSITE

  

PRINTS