CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021537
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 UPF0364 protein C6orf211 
Protein Synonyms/Alias
  
Gene Name
 C6orf211 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
31RIPQILTKVIDTLHRubiquitination[1]
40IDTLHRHKSEFFEKHacetylation[2, 3, 4]
56EEGVEAEKKAISLLSacetylation[4]
73RNELQTDKPFIPLVEacetylation[2]
105LLNESDGKSRWFYSPubiquitination[5]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Lysine acetylation targets protein complexes and co-regulates major cellular functions.
 Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M.
 Science. 2009 Aug 14;325(5942):834-40. [PMID: 19608861]
 [3] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [5] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
 MOD_RES 2 2 N-acetylalanine.
 MOD_RES 40 40 N6-acetyllysine.  
Keyword
 Acetylation; Complete proteome; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 441 AA 
Protein Sequence
MAVVPASLSG QDVGSFAYLT IKDRIPQILT KVIDTLHRHK SEFFEKHGEE GVEAEKKAIS 60
LLSKLRNELQ TDKPFIPLVE KFVDTDIWNQ YLEYQQSLLN ESDGKSRWFY SPWLLVECYM 120
YRRIHEAIIQ SPPIDYFDVF KESKEQNFYG SQESIIALCT HLQQLIRTIE DLDENQLKDE 180
FFKLLQISLW GNKCDLSLSG GESSSQNTNV LNSLEDLKPF ILLNDMEHLW SLLSNCKKTR 240
EKASATRVYI VLDNSGFELV TDLILADFLL SSELATEVHF YGKTIPWFVS DTTIHDFNWL 300
IEQVKHSNHK WMSKCGADWE EYIKMGKWVY HNHIFWTLPH EYCAMPQVAP DLYAELQKAH 360
LILFKGDLNY RKLTGDRKWE FSVPFHQALN GFHPAPLCTI RTLKAEIQVG LQPGQGEQLL 420
ASEPSWWTTG KYGIFQYDGP L 441 
Gene Ontology
  
Interpro
 IPR002791; DUF89. 
Pfam
 PF01937; DUF89 
SMART
  
PROSITE
  
PRINTS