UniProt Accession

 Q3UCW0_MOUSE; Q3UCW0 

Genbank Protein ID

 AK146602; AK150369; CH466603 

Genbank Nucleotide ID

 BAE27296.1; BAE29502.1; EDL22949.1 

Protein Name

 MCG123182 

Protein Synonyms/Alias

  

Gene Name

 Tsg101 

Gene Synonyms/Alias

 mCG_123182 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
36	IAMYKDLKPVLDSYV	ubiquitination	[1]
238	LISAVSDKLRWRMKE	ubiquitination	[1]
244	DKLRWRMKEEMDGAQ	ubiquitination	[1]
362	IDLDVFLKHVRLLSR	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

  

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 391 AA 

Protein Sequence

Gene Ontology

 GO:0005769; C:early endosome; IEA:Compara.
 GO:0005770; C:late endosome; IEA:Compara.
 GO:0005730; C:nucleolus; IEA:Compara.
 GO:0005634; C:nucleus; IC:MGI.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0003714; F:transcription corepressor activity; IDA:MGI.
 GO:0007050; P:cell cycle arrest; IDA:MGI.
 GO:0006464; P:cellular protein modification process; IEA:InterPro.
 GO:0030216; P:keratinocyte differentiation; IDA:MGI.
 GO:0008285; P:negative regulation of cell proliferation; IDA:MGI.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI.
 GO:0015031; P:protein transport; IEA:InterPro.
 GO:0001558; P:regulation of cell growth; IDA:MGI.
 GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IEA:Compara. 

Interpro

 IPR017916; Steadiness_box.
 IPR016135; UBQ-conjugating_enzyme/RWD.
 IPR008883; UEV_N. 

Pfam

 PF05743; UEV
 PF09454; Vps23_core 

SMART

  

PROSITE

 PS51312; SB
 PS51322; UEV 

PRINTS