CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035810
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Wapal 
Protein Synonyms/Alias
  
Gene Name
 Wapal 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
7*MTSRFGKTYSRKGGacetylation[1]
52GQKRPNFKPDIQEIPacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1198 AA 
Protein Sequence
MTSRFGKTYS RKGGNGSSKF DEVFSNKRTT LSTKWGETTF MAKLGQKRPN FKPDIQEIPK 60
KPKVEEEDTG DPFGFDSDDE SLPVSSKSLA QGKGSSYSES SEAVQLEEVT SVLEANSKCS 120
HAVGEDSFAS DRCLLVEDSL IGKEKNTNRI PEDNANKSSC TKLITSDKVE NFSEEHEKNS 180
HHFHKNAEDS TKKPNAETVA ASECKADETK TSDTWNSQSA KRTESPSESC PVKGSVRTGL 240
YEWDNDFEDI RSEDCILSLD NDSLLEMKDE DLKNRIGGLE NLNEAFEEDI IQSVLRPSNC 300
RTYCRANKAK SSQGTSNFDK LMDGTSQTLA KANSESSKDG LNQAKKGSVS CGTSFRGTVG 360
RTRDYTVLHP SCLSVCNVTI QDTMERSMDE FTASTPADLG EAGRLRKKAD IATSKTTTRF 420
RPSNTKSKKD VKLEFFGFED HDETGGDEGG SGSSNYKIKY FGFDDLSESE DDDDDDCQVE 480
RKKDKKRTKT APSPSQQPPP ESSDNSQDSQ SSTNNAENLD FTEDLPGVPE SVKKPISKQG 540
DKSKENTRKI FSGPKRSPTK AVYNARHWNH PDSQELPGPP IVKPQSVTVR LSSKEPNQKD 600
DGVFKAPAPP LKVIKTVTIP TQPYQEIVTA LKCRKEDKEL YTVVQHVKHF NDVVEFGENQ 660
EFTDDIEYLL SGLKSTQPLN TRCLSVISLA TKCAMPSFRM HLRAHGMVAM VFKTLDDSQH 720
HQNLSLCTAA LMYILSRDRL NMDLDRASLD LMIRLLELEQ DASSAKLLNE KDMNKIKEKI 780
RRLCETVHNK HLDLENITTG HLAMETLLSL TSKRAGDWFK EELRLLGGLD HIVDKVKECV 840
DHLSRDEDEE KLVASLWGAE RCLRVLESVT VHNPENQSYL IAYKDSQLII SSAKALQHCE 900
DLIQQYNRAE NSICIADSKP LPYQNVTNHV GKAVEDCMRA IIGVLLNLTN DNEWGSTKTG 960
EQEGLIGTAM NCVLQVPKYL PQEQRFDIRV LGLGLLINLV EYSARNRHCL VNMETSCSFD 1020
SSFSSGEGDH NLRLAGQVHA VQALVQLFLE RERAAQLAES KTDELIKDAP TTQHDKSGEW 1080
QETSGEIQWV STEKTDGAEE KQKKEDEDEE LDLNKALQHA GKHMEDCIVA SYTALLLGCL 1140
CQESPINVTT VREYLPEGDF SIMTEMLKKF LSFMNLTCAV GTTGQKSISR VIEYLEHC 1198 
Gene Ontology
 GO:0000785; C:chromatin; IEA:Compara.
 GO:0008278; C:cohesin complex; IEA:Compara.
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0015630; C:microtubule cytoskeleton; IEA:Compara.
 GO:0000795; C:synaptonemal complex; IEA:Compara.
 GO:0035562; P:negative regulation of chromatin binding; IEA:Compara.
 GO:0008156; P:negative regulation of DNA replication; IEA:Compara.
 GO:0045875; P:negative regulation of sister chromatid cohesion; IEA:Compara.
 GO:0071168; P:protein localization to chromatin; IEA:Compara.
 GO:0071922; P:regulation of cohesin localization to chromatin; IEA:Compara.
 GO:0009636; P:response to toxic substance; IEA:Compara. 
Interpro
 IPR016024; ARM-type_fold.
 IPR012502; WAPL_metazoan_plants.
 IPR022771; WAPL_prot. 
Pfam
 PF07814; WAPL 
SMART
  
PROSITE
 PS51271; WAPL 
PRINTS