CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030049
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 CD34 antigen (Predicted) 
Protein Synonyms/Alias
 CD34 antigen isoform 1; Protein Cd34 
Gene Name
 Cd34 
Gene Synonyms/Alias
 Cd34_predicted; rCG_20068 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
263SKLQLMEKHQSDLRKacetylation[1]
278LGIQSFNKQDLGSHQacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 386 AA 
Protein Sequence
MPVHRGARAG LLLPWGWVAL CLMSLLHLNN LTSVASENST QGVFPPVPTN ESTEESITSS 60
IPGSTSHYYL IGQDSNKTTP AISETTVNFT ATPGTPSGSG TPHTFSQPQT YPTVTLPTTS 120
DSTSTPEVEH STWNTSLPSV NVSDYSPNNV SSEMISTTEP CAHTSSSVPS IIKGDIKCSG 180
IRGVPFTQGI CLELSEASSC EEFKKERGEE LMQILCKKEE TEADAGTSVC SLNLAQSEVR 240
PECLLMVLAN STELSSKLQL MEKHQSDLRK LGIQSFNKQD LGSHQSYSRK TLIALVTSGV 300
LLAILGTTGY FLMNRRSWSP TGERLGEDPY YTENGGGQGY SSGPGTSPET QGKANVTRGA 360
QENGTGQATS RNGHSARQHV VADTEL 386 
Gene Ontology
 GO:0016324; C:apical plasma membrane; IDA:UniProtKB.
 GO:0009925; C:basal plasma membrane; IDA:UniProtKB.
 GO:0009897; C:external side of plasma membrane; ISS:UniProtKB.
 GO:0036053; C:glomerular endothelium fenestra; IDA:UniProtKB.
 GO:0045171; C:intercellular bridge; ISS:UniProtKB.
 GO:0005764; C:lysosome; IDA:UniProtKB.
 GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
 GO:0030246; F:carbohydrate binding; ISS:UniProtKB.
 GO:0016337; P:cell-cell adhesion; ISS:UniProtKB.
 GO:0001935; P:endothelial cell proliferation; ISS:UniProtKB.
 GO:0071971; P:extracellular vesicular exosome assembly; ISS:UniProtKB.
 GO:0003094; P:glomerular filtration; IEP:UniProtKB.
 GO:0006536; P:glutamate metabolic process; ISS:UniProtKB.
 GO:0071425; P:hematopoietic stem cell proliferation; ISS:UniProtKB.
 GO:0035759; P:mesangial cell-matrix adhesion; IEP:UniProtKB.
 GO:0030195; P:negative regulation of blood coagulation; ISS:UniProtKB.
 GO:1900035; P:negative regulation of cellular response to heat; ISS:UniProtKB.
 GO:1900038; P:negative regulation of cellular response to hypoxia; ISS:UniProtKB.
 GO:0010629; P:negative regulation of gene expression; ISS:UniProtKB.
 GO:1900041; P:negative regulation of interleukin-2 secretion; ISS:UniProtKB.
 GO:0060547; P:negative regulation of necrotic cell death; ISS:UniProtKB.
 GO:0045019; P:negative regulation of nitric oxide biosynthetic process; ISS:UniProtKB.
 GO:0032720; P:negative regulation of tumor necrosis factor production; ISS:UniProtKB.
 GO:0038001; P:paracrine signaling; ISS:UniProtKB.
 GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.
 GO:0071657; P:positive regulation of granulocyte colony-stimulating factor production; ISS:UniProtKB.
 GO:0032733; P:positive regulation of interleukin-10 production; ISS:UniProtKB.
 GO:0042482; P:positive regulation of odontogenesis; ISS:UniProtKB.
 GO:0071636; P:positive regulation of transforming growth factor beta production; ISS:UniProtKB.
 GO:2001214; P:positive regulation of vasculogenesis; ISS:UniProtKB.
 GO:0008217; P:regulation of blood pressure; ISS:UniProtKB.
 GO:0001894; P:tissue homeostasis; ISS:UniProtKB. 
Interpro
 IPR008083; CD34.
 IPR013836; CD34/Podocalyxin. 
Pfam
 PF06365; CD34_antigen 
SMART
  
PROSITE
  
PRINTS
 PR01700; CD34ANTIGEN.