CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029230
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Intersectin 1 long form variant 4 
Protein Synonyms/Alias
 Intersectin 1 short form variant 11; Intersectin-1 
Gene Name
 ITSN1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
658RRAQERDKQWLEHVQubiquitination[1]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; SH3 domain. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1015 AA 
Protein Sequence
MAQFPTPFGG SLDIWAITVE ERAKHDQQFH SLKPISGFIT GDQARNFFFQ SGLPQPVLAQ 60
IWALADMNND GRMDQVEFSI AMKLIKLKLQ GYQLPSALPP VMKQQPVAIS SAPAFGMGGI 120
ASMPPLTAVA PVPMGSIPVV GMSPTLVSSV PTAAVPPLAN GAPPVIQPLP AFAHPAATLP 180
KSSSFSRSGP GSQLNTKLQK AQSFDVASVP PVAEWAVPQS SRLKYRQLFN SHDKTMSGHL 240
TGPQARTILM QSSLPQAQLA SIWNLSDIDQ DGKLTAEEFI LAMHLIDVAM SGQPLPPVLP 300
PEYIPPSFRR VRSGSGISVI SSTSVDQRLP EEPVLEDEQQ QLEKKLPVTF EDKKRENFER 360
GNLELEKRRQ ALLEQQRKEQ ERLAQLERAE QERKERERQE QERKRQLELE KQLEKQRELE 420
RQREEERRKE IERREAAKRE LERQRQLEWE RNRRQELLNQ RNKEQEDIVV LKAKKKTLEF 480
ELEALNDKKH QLEGKLQDIR CRLTTQRQEI ESTNKSRELR IAEITHLQQQ LQESQQMLGR 540
LIPEKQILND QLKQVQQNSL HRDSLVTLKR ALEAKELARQ HLRDQLDEVE KETRSKLQEI 600
DIFNNQLKEL REIHNKQQLQ KQKSMEAERL KQKEQERKII ELEKQKEEAQ RRAQERDKQW 660
LEHVQQEDEH QRPRKLHEEE KLKREESVKK KDGEEKGKQE AQDKLGRLFH QHQEPAKPAV 720
QAPWSTAEKG PLTISAQENV KVVYYRALYP FESRSHDEIT IQPGDIVMVD ESQTGEPGWL 780
GGELKGKTGW FPANYAEKIP ENEVPAPVKP VTDSTSAPAP KLALRETPAP LAVTSSEPST 840
TPNNWADFSS TWPTSTNEKP ETDNWDAWAA QPSLTVPSAG QLRQRSAFTP ATATGSSPSP 900
VLGQGEKVEG LQAQALYPWR AKKDNHLNFN KNDVITVLEQ QDMWWFGEVQ GQKGWFPKSY 960
VKLISGPIRK STSMDSGSSE SPASLKRVAS PAAKPVVSGE GLWNCWENRE FRKKT 1015 
Gene Ontology
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0006897; P:endocytosis; IEA:InterPro. 
Interpro
 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom.
 IPR000261; EPS15_homology.
 IPR026813; ITSN1.
 IPR001452; SH3_domain. 
Pfam
 PF00018; SH3_1 
SMART
 SM00054; EFh
 SM00027; EH
 SM00326; SH3 
PROSITE
 PS00018; EF_HAND_1
 PS50222; EF_HAND_2
 PS50031; EH
 PS50002; SH3 
PRINTS