CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-045124
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Kelch-like ECH-associated protein 1 
Protein Synonyms/Alias
  
Gene Name
 KEAP1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
163VTMEPCRKQIDQQNCubiquitination[1, 2, 3, 4]
Reference
 [1] Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin.
 Oshikawa K, Matsumoto M, Oyamada K, Nakayama KI.
 J Proteome Res. 2012 Feb 3;11(2):796-807. [PMID: 22053931]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Kelch repeat; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 172 AA 
Protein Sequence
XCYNPMTNQW SPCAPMSVPR NRIGVGVIDG HIYAVGGSHG CIHHNSVERY EPERDEWHLV 60
APMLTRRIGV GVAVLNRLLY AVGGFDGTNR LNSAECYYPE RNEWRMITAM NTIRSGAGGY 120
DGHTFLDSVE CYDPDTDTWS EVTRMTSGRS GVGVAVTMEP CRKQIDQQNC TC 172 
Gene Ontology
  
Interpro
 IPR015916; Gal_Oxidase_b-propeller.
 IPR006652; Kelch_1. 
Pfam
 PF01344; Kelch_1 
SMART
 SM00612; Kelch 
PROSITE
  
PRINTS