CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037365
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Ankyrin repeat and KH domain-containing protein 1 
Protein Synonyms/Alias
  
Gene Name
 ANKHD1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
1424TDKELLKKCHQCVETubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 ANK repeat; Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1565 AA 
Protein Sequence
MLTDSGGGGT SFEEDLDSVA PRSAPAGASE PPPPGGVGLG IRTVRLFGEA GPASGVGSSG 60
GGGSGSGTGG GDAALDFKLA AAVLRTGGGG GASGSDEDEV SEVESFILDQ EDLDNPVLKT 120
TSEIFLSSTA EGADLRTVDP ETQARLEALL EAAGIGKLST ADGKAFADPE VLRRLTSSVS 180
CALDEAAAAL TRMKAENSHN AGQVDTRSLA EACSDGDVNA VRKLLDEGRS VNEHTEEGES 240
LLCLACSAGY YELAQVLLAM HANVEDRGNK GDITPLMAAS SGGYLDIVKL LLLHDADVNS 300
QSATGNTALT YACAGGFVDI VKVLLNEGAN IEDHNENGHT PLMEAASAGH VEVARVLLDH 360
GAGINTHSNE FKESALTLAC YKGHLDMVRF LLEAGADQEH KTDEMHTALM EACMDGHVEV 420
ARLLLDSGAQ VNMPADSFES PLTLAACGGH VELAALLIER GANLEEVNDE GYTPLMEAAR 480
EGHEEMVALL LAQGANINAQ TEETQETALT LACCGGFSEV ADFLIKAGAD IELGCSTPLM 540
EASQEGHLEL VKYLLASGAN VHATTATGDT ALTYACENGH TDVADVLLQA GADLDKQEDM 600
KTILEGIDPA KHQEHESEGG RTPLMKAARA GHLCTVQFLI SKGANVNRAT ANNDHTVVSL 660
ACAGGHLAVV ELLLAHGADP THRLKDGSTM LIEAAKGGHT NVVSYLLDYP NNVLSVPTTD 720
VSQLPPPSQD QSQVPRVPTH TLAMVVPPQE PDRTSQENSP ALLGVQKGTS KQKSSSLQVA 780
DQDLLPSFHP YQPLECIVEE TEGKLNELGQ RISAIEKAQL KSLELIQGEP LNKDKIEELK 840
KNREEQVQKK KKILKELQKV ERQLQMKTQQ QFTKEYLETK GQKDTVSLHQ QCSHRGVFPE 900
GEGDGSLPED HFSELPQVDT ILFKDNDVDD EQQSPPSAEQ IDFVPVQPLS SPQCNFSSDL 960
GSNGTNSLEL QKVSGNQQIV GQPQIAITGH DQGLLVQEPD GLMVATPAQT LTDTLDDLIA 1020
AVSTRVPTGS NSSSQTTECL TPESCSQTTS NVASQSMPPV YPSVDIDAHT ESNHDTALTL 1080
ACAGGHEELV SVLIARDAKI EHRDKKGFTP LILAATAGHV GVVEILLDKG GDIEAQSERT 1140
KDTPLSLACS GGRQEVVDLL LARGANKEHR NVSDYTPLSL AASGGYVNII KILLNAGAEI 1200
NSRTGSKLGI SPLMLAAMNG HVPAVKLLLD MGSDINAQIE TNRNTALTLA CFQGRAEVVS 1260
LLLDRKANVE HRAKTGLTPL MEAASGGYAE VGRVLLDKGA DVNAPPVPSS RDTALTIAAD 1320
KGHYKFCELL IHRGAHIDVR NKKGNTPLWL ASNGGHFDVV QLLVQAGADV DAADNRKITP 1380
LMSAFRKGHV KVVQYLVKEV NQFPSDIECM RYIATITDKE LLKKCHQCVE TIVKAKDQQA 1440
AEANKNASIL LKELDLEKSR EESRKQALAA KREKRKEKRK KKKEEQKRKQ EEDEENKPKE 1500
NSELPEDEDE EENDEDVEQE VPIEPPSATT TTTIGISATS ATFTNVFGKK RANVVTTPST 1560
NRKNK 1565 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005634; C:nucleus; IDA:HPA. 
Interpro
 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom. 
Pfam
 PF12796; Ank_2 
SMART
 SM00248; ANK 
PROSITE
 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT 
PRINTS
 PR01415; ANKYRIN.