CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015009
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein PRRC2A 
Protein Synonyms/Alias
 HLA-B-associated transcript 2; Proline-rich and coiled-coil-containing protein 2A 
Gene Name
 Prrc2a 
Gene Synonyms/Alias
 Bat2 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
27LNLFDTYKGKSLEIQacetylation[1]
35GKSLEIQKPAVAPRHacetylation[1]
49HGLQSLGKVAIARRMacetylation[1]
958RRAGPIKKPPPPVKAacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 May play a role in the regulation of pre-mRNA splicing (By similarity). 
Sequence Annotation
 REPEAT 41 95 1-1.
 REPEAT 98 154 1-2.
 REPEAT 281 337 1-3.
 REPEAT 337 429 2-1.
 REPEAT 487 560 2-2.
 REPEAT 1760 1815 1-4.
 REPEAT 1920 1969 3-1.
 REPEAT 1986 2035 3-2.
 REPEAT 2061 2110 3-3.
 REGION 41 1815 4 X 57 AA type A repeats.
 REGION 337 560 2 X type B repeats.
 REGION 1920 2110 3 X 50 AA type C repeats.
 MOD_RES 27 27 N6-acetyllysine (By similarity).
 MOD_RES 166 166 Phosphoserine (By similarity).
 MOD_RES 342 342 Phosphoserine (By similarity).
 MOD_RES 350 350 Phosphoserine (By similarity).
 MOD_RES 378 378 Phosphoserine (By similarity).
 MOD_RES 381 381 Phosphoserine (By similarity).
 MOD_RES 455 455 Phosphoserine (By similarity).
 MOD_RES 609 609 Phosphothreonine (By similarity).
 MOD_RES 760 760 Phosphoserine (By similarity).
 MOD_RES 762 762 Phosphoserine (By similarity).
 MOD_RES 765 765 Phosphoserine (By similarity).
 MOD_RES 783 783 Phosphothreonine (By similarity).
 MOD_RES 809 809 Phosphoserine (By similarity).
 MOD_RES 1007 1007 Phosphoserine (By similarity).
 MOD_RES 1088 1088 Phosphoserine (By similarity).
 MOD_RES 1092 1092 Phosphoserine (By similarity).
 MOD_RES 1095 1095 Phosphoserine (By similarity).
 MOD_RES 1097 1097 Phosphotyrosine (By similarity).
 MOD_RES 1113 1113 Phosphoserine (By similarity).
 MOD_RES 1150 1150 Phosphoserine (By similarity).
 MOD_RES 1199 1199 N6-acetyllysine (By similarity).
 MOD_RES 1222 1222 Phosphoserine (By similarity).
 MOD_RES 1307 1307 Phosphoserine (By similarity).
 MOD_RES 1354 1354 Phosphothreonine (By similarity).
 MOD_RES 1406 1406 Phosphothreonine.
 MOD_RES 2117 2117 Phosphoserine (By similarity).  
Keyword
 Acetylation; Complete proteome; Cytoplasm; Nucleus; Phosphoprotein; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2161 AA 
Protein Sequence
MSDRSGPTAK GKDGKKYSSL NLFDTYKGKS LEIQKPAVAP RHGLQSLGKV AIARRMPPPA 60
NLPSLKAENK GNDPNVSLVP KDGTGWASKQ EQSDPKSSDA STAQPPESQP LPASQTPASN 120
QPKRPPTAPE NTPSVPSGVK SWAQASVTHG AHGDGGRASS LLSRFSREEF PTLQAAGDQD 180
KAAKERESAE QSSGPGPSLR PQNSTTWRDG GGRGPDELEG PDSKLHHGHD PRGGLQPSGP 240
PQFPPYRGMM PPFMYPPYLP FPPPYGPQGP YRYPTPDGPS RFPRVAGPRG SGPPMRLVEP 300
VGRPSILKED NLKEFDQLDQ ENDDGWAGAH EEVDYTEKLK FSDEEDGRDS DEEGAEGHKD 360
SQSAAGEEPE TDGKKGTSPG SELPPPKTAW TENSRPSETE PAAPPIPKPP PPPPHRGPVG 420
NWGPPGDYPD RGGPPCKPPA PEDEDEAWRQ RRKQSSSEIS LAVERARRRR EEEERRMQEE 480
RRAACAEKLK RLDEKFGAPD KRLKAEPAAP PVTPPAPALP PVVPKETPTP PALPPTPTPT 540
PEKDPEEPAH APPVQSAPTQ AGPPAPTPVS GGGTASSTSS GSFEASPAEP QLPSKEGPEP 600
PEEVPAPTTP PAPKVEPKGD GVGPTRQPPS QGLGYPKYQK SLPPRFQRQQ QEQLLKQQQQ 660
QQWQQQQQQQ GTAPPAPVPP SPPQPVTLGA VPAPQAPPPP PKALYPGALG RPPPMPPMNF 720
DPRWMMIPPY VDPRLLQGRP PLDFYPPGVH PSGLVPRERS DSGGSSSEPF ERHAPPLLRE 780
RGTPPVDPKL AWVGDVFTTT PTDPRPLTSP LRQAADEEEK SLRSETPPVP PPPPYLANYP 840
GFPENGTPGP PISRFPLEES APPGPRPLPW PPGNDEAAKM QAPPPKKEPP KEEPAQLSGP 900
EAGRKPARGV GGGGQGPPPP RRENRTETRW GPRPGSCRRG IPPEDPGVPP RRAGPIKKPP 960
PPVKADELPP KSLEPGDETP KAPKPDALKT AKGKVGPKET PAGGNLSPAP RLRRDYSYER 1020
VGPTSCRGRG RGEYFARGRG FRGTYGGRGR GARSREFRSY REFRGDDGRG GGSGGTNHPS 1080
APRGRTASET RSEGSEYEEI PKRRRQRGSE TGSETHESDL APSDKEAPPP KEGVLAQVPL 1140
APPQPGAPPS PAPARFSTAR GGRVFTPRGV PSRRGRGGGR PPPVCSGWSP PAKSLVPKKP 1200
PTGPLPPNKE PLKEKLISGP LSPMSRAGNM GVGMEDGERP RRRRHGRAQQ QDKPPRFRRL 1260
KQDRENAARG TDGKPPPLTL PASTPAPTET LATVAAPPPP RRTAAKSPDL SNQNSDQANE 1320
EWETASESSD FASERRGDKE TPPAALITSK AVGTPGGNSG GAGPGISTMS RGDLSQRAKD 1380
LSKRSFSSQR PGMDRQNRRP GAGGKTGGGG SSGGGGAGPG GRTGPGRGDK RSWPSPKNRS 1440
RPPEERPPGL PLPPPPPSSS AVFRLDQVIH SNPAGIQQAL AQLSSRQGNV TAPGGHPRPK 1500
PGPPQAPQGS SPRPPTHYDP PRASNAISSD PHFEEPGPMV RGVGGTPRDS AGVNPFPPKR 1560
RERPPRKPEL LQEETVPASH SSGFLGSKPE VPGPQEESRD SGTEALTPHI WNRLHTATSR 1620
KSYQPGSIEP WMEPLSPFED VAGTEMSQSD SGVDLSGGSQ VSSGPCSQRS SPDGGLKGSA 1680
EGPPRRPGGP SPLKAVPGES SSASEPSEPH RRRPPASHEG ERKELPREQP LPPGPIGTER 1740
SQRTDRGPEP GPLRPAHRAG SQVEFGTTNK DSDLCLVVGD TLKGEKELAA SATEAVPVSR 1800
DWELLPSASA SAEPQAKSLG SGQCGPEPSP SGQRLYPEVF YGSPGPPNSQ VSGGAPIDSQ 1860
LHPSSGGFRP GTPSVHQYRS QPLYLPPGPA PPSALLSGVA LKGQFLDFSA LQATELGKLP 1920
AGGVLYPPPS FLYSAAFCPS PLPDPPLLQV RQDLPSPSDF YSTPLQPGGQ SGFLPSGAPA 1980
QQMLLPVVDS QLPVVNFGSL PPAPPPAPPP LSLLPVGPAL QPPNLAVRPP PAPAARVLPS 2040
PARPFPASLG RAELHPVELK PFQDYRKLSS NLGGPGSSRA PPSGRSFSGL NSRLKAPPST 2100
YSGVFRTQRI DLYQQASPPD ALRWMPKPWE RTGPPSREGP PRRAEEPGPR GEKEPGLPPP 2160
R 2161 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. 
Interpro
 IPR009738; BAT2_N. 
Pfam
 PF07001; BAT2_N 
SMART
  
PROSITE
  
PRINTS