UniProt Accession

 PSB6_MOUSE; Q60692; Q3V240; Q60693; Q8BJX9; Q91VH5 

Genbank Protein ID

 U13393; U13394; AK078437; AK132042; AK167123; AK167227; AL592547; BC013897 

Genbank Nucleotide ID

 AAA75375.1; AAA75376.1; BAC37272.1; BAE20959.1; BAE39271.1; BAE39351.1; CAI24014.1; AAH13897.1 

Protein Name

 Proteasome subunit beta type-6 

Protein Synonyms/Alias

 Low molecular mass protein 19; Macropain delta chain; Multicatalytic endopeptidase complex delta chain; Proteasome delta chain; Proteasome subunit Y 

Gene Name

 Psmb6 

Gene Synonyms/Alias

 Lmp19 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
66	IANRVTDKLTPIHDH	acetylation	[1]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 

Functional Description

 The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. May catalyze basal processing of intracellular antigens. 

Sequence Annotation

 ACT_SITE 34 34 Nucleophile (By similarity).
 MOD_RES 2 2 N-acetylalanine (By similarity).  

Keyword

 3D-structure; Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Hydrolase; Nucleus; Polymorphism; Protease; Proteasome; Reference proteome; Threonine protease; Zymogen. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 238 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; TAS:Reactome.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0005839; C:proteasome core complex; IDA:UniProtKB.
 GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
 GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro. 

Interpro

 IPR000243; Pept_T1A_subB.
 IPR016050; Proteasome_bsu_CS.
 IPR001353; Proteasome_sua/b.
 IPR023333; Proteasome_suB-type. 

Pfam

 PF00227; Proteasome 

SMART

  

PROSITE

 PS00854; PROTEASOME_B_1
 PS51476; PROTEASOME_B_2 

PRINTS

 PR00141; PROTEASOME.