| Tag | Content |
|---|
| CPLM ID | CPLM-016699 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Condensin complex subunit 2 |
Protein Synonyms/Alias | Barren homolog protein 1; Chromosome-associated protein H; mCAP-H; Non-SMC condensin I complex subunit H; XCAP-H homolog |
Gene Name | Ncaph |
Gene Synonyms/Alias | Brrn; Brrn1; Caph |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 638 | KMDMKKLKQSMWSLL | acetylation | [1] |
|
Reference | [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways. Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y. Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [ PMID: 22826441] |
Functional Description | Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (By similarity). |
Sequence Annotation | MOD_RES 12 12 Phosphoserine (By similarity).
MOD_RES 46 46 Phosphothreonine (By similarity).
MOD_RES 67 67 Phosphoserine (By similarity).
MOD_RES 75 75 Phosphoserine (By similarity).
MOD_RES 78 78 Phosphoserine (By similarity).
MOD_RES 83 83 Phosphoserine (By similarity).
MOD_RES 91 91 Phosphoserine (By similarity).
MOD_RES 195 195 Phosphoserine (By similarity).
MOD_RES 425 425 Phosphoserine (By similarity).
MOD_RES 587 587 Phosphothreonine (By similarity).
MOD_RES 627 627 N6-acetyllysine (By similarity). |
Keyword | Acetylation; Cell cycle; Cell division; Chromosome; Complete proteome; Cytoplasm; DNA condensation; Mitosis; Nucleus; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 731 AA |
Protein Sequence | MRIPRSETMN SSFLKARGQQ DVLSSPLERV PPASRPGKAP LGTPKTPVLE DFPQNDDEKE 60
RMQRRRSRVF DLQFSTDSIH LASPNRNIDV STTISKFTNT QITEHYSTCI KLSSENKITT 120
KNAFGLHLID FMSEILKQKD AEPTNFKVAA GTLDASTKIY AVRVDAVHAD VYRVLGGLGK 180
DTPPQGEESH SGDGSTLETE RTKKPAKPKK KQSCKTIEQN LSNINVSEAD GKCAVDPMFQ 240
KTAASFDECS TTGVFLSTLH CQDYRSELLF PSDMQTLSSG EPLELPDLGF VDMTDLEASL 300
QQCVEDRPLC PSLAGFQFTK WDSETHNESV SALVDKFKKN DQVFDINAEA EDDEEDVPDG 360
PLVEDFVDND EPDLSAAGDH EEFRSWKELC QVQSNQEEVI SLEDRDIQVM CSFLSMKPGE 420
YSYFSPRTMK MWAGPDHWRF RPRPKQDATS CTEHKKKSAK KDFEINFDDD IDFDAYFQKT 480
KAATILTKST LENQNWKATT LPTDFHYETD NLIQLHLKPG KRSLKMDQDQ KAKTEHYEEI 540
EDYDYNNPND TSNYCPGLQA ADSDYEEADD LFADPVGTLD LESDPKTTQE NGHISPENQG 600
VDITTYQELN LVAEPQKVNK IEIHYAKTAK KMDMKKLKQS MWSLLTKFSR KEADTEANHT 660
ESGQEGAPEE VADEKKLSGL TKDLQTRLPP LMAQNLSIPL AFACLLHLAN EKNLKLEGTE 720
DLSDVLVMQG D 731 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |