CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-022349
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ankyrin repeat domain-containing protein 10 
Protein Synonyms/Alias
  
Gene Name
 ANKRD10 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
131EGETPIHKAARSGSLubiquitination[1]
225DSEDFGVKKARTEAQubiquitination[1, 2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
 REPEAT 21 50 ANK 1.
 REPEAT 57 86 ANK 2.
 REPEAT 91 120 ANK 3.
 REPEAT 124 153 ANK 4.  
Keyword
 Alternative splicing; ANK repeat; Complete proteome; Polymorphism; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 420 AA 
Protein Sequence
MSAAGAGAGV EAGFSSEELL SLRFPLHRAC RDGDLATLCS LLQQTPHAHL ASEDSFYGWT 60
PVHWAAHFGK LECLVQLVRA GATLNVSTTR YAQTPAHIAA FGGHPQCLVW LIQAGANINK 120
PDCEGETPIH KAARSGSLEC ISALVANGAH VDLRNASGLT AADIAQTQGF QECAQFLLNL 180
QNCHLNHFYN NGILNGGHQN VFPNHISVGT NRKRCLEDSE DFGVKKARTE AQSLDSAVPL 240
TNGDTEDDAD KMHVDREFAV VTDMKNSSSV SNTLTNGCVI NGHLDFPSTT PLSGMESRNG 300
QCLTGTNGIS SGLAPGQPFP SSQGSLCISG TEEPEKTLRA NPELCGSLHL NGSPSSCIAS 360
RPSWVEDIGD NLYYGHYHGF GDTAESIPEL NSVVEHSKSV KVQERYDSAV LGTMHLHHGS 420 
Gene Ontology
  
Interpro
 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom. 
Pfam
 PF12796; Ank_2 
SMART
 SM00248; ANK 
PROSITE
 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT 
PRINTS