CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-045590
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Uncharacterized protein 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
348VFVSPLAKKLAAEKGacetylation[1]
354AKKLAAEKGIDLTQVacetylation[1]
362GIDLTQVKGTGPEGRacetylation[1]
373PEGRIIKKDIDSFVPacetylation[1]
447GEVLLVRKELNKMLEacetylation[1]
451LVRKELNKMLEGKGKacetylation[1]
458KMLEGKGKISVNDFIacetylation[1]
537ASKAREGKLQPHEFQacetylation[1]
621AQWLAEFKKYLEKPVacetylation[1]
622QWLAEFKKYLEKPVTacetylation[1]
626EFKKYLEKPVTMLL*acetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Acyltransferase; Complete proteome; Lipoyl; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 632 AA 
Protein Sequence
MWPVCARRVQ SAVPRAGFRA RWATLKGPRT GPAAVRCSSG IPSYGVRSLC GWSYGSATVP 60
RNRILQQLLG SPSRRSYSLP PHQKVPLPSL FPTMQAGTIA RWEKKEGEKI SEGDLIAEVE 120
TDKATVGFES LEERYMAKIL VPEGTRDVPV GSIICITVEK PQDIEAFKNY TLDSATAATQ 180
AAPAPAAAPA AAPAAPSANA PGNSYPVHMQ IVLPALSPTM TMGTFQRWEK EVGEKLSEGD 240
LLAEIETDKA TIGFEVQEEG YLAKILVPEG TRDVPLGTPL CITVEKQEDI AAFADYRPTE 300
VTSLKPQAPP PVPPPVAAVP PTPQPLAPTP SAAPAEPKGR VFVSPLAKKL AAEKGIDLTQ 360
VKGTGPEGRI IKKDIDSFVP TKAAPAAAAA APPGPRVAPT PAGVFIDIPI SNIRRVIAQR 420
LMQSKQTIPH YYPSVDVNMG EVLLVRKELN KMLEGKGKIS VNDFIIKASA LACLKVPEAN 480
SSWMDTVIRQ NHVVDVSVAV STPAGLITPI VFNAHIKGLE TIASDVVSLA SKAREGKLQP 540
HEFQGGTFTI SNLGMFGIKN FSAIINPPQA CILAIGASED KLIPADNEKG FDVASVMSVT 600
LSCDHRVVDG AVGAQWLAEF KKYLEKPVTM LL 632 
Gene Ontology
 GO:0045254; C:pyruvate dehydrogenase complex; IEA:InterPro.
 GO:0004742; F:dihydrolipoyllysine-residue acetyltransferase activity; IEA:InterPro.
 GO:0006090; P:pyruvate metabolic process; IEA:InterPro. 
Interpro
 IPR003016; 2-oxoA_DH_lipoyl-BS.
 IPR001078; 2-oxoacid_DH_actylTfrase.
 IPR000089; Biotin_lipoyl.
 IPR023213; CAT-like_dom.
 IPR004167; E3-bd.
 IPR006257; LAT1.
 IPR011053; Single_hybrid_motif. 
Pfam
 PF00198; 2-oxoacid_dh
 PF00364; Biotin_lipoyl
 PF02817; E3_binding 
SMART
  
PROSITE
 PS50968; BIOTINYL_LIPOYL
 PS00189; LIPOYL 
PRINTS