UniProt Accession

 FABD_MYCTU; P63458; L0TAL7; Q10501 

Genbank Protein ID

 AE000516; AL123456 

Genbank Nucleotide ID

 AAK46587.1; CCP45023.1 

Protein Name

 Malonyl CoA-acyl carrier protein transacylase 

Protein Synonyms/Alias

 MCT 

Gene Name

 fabD 

Gene Synonyms/Alias

 Rv2243; MT2303; MTCY427.24 

Created Date

 July 27, 2013 

Organism

 Mycobacterium tuberculosis 

NCBI Taxa ID

 1773 

Lysine Modification

Position	Peptide	Type	References
173	GRLTALEKLAEDPPA	pupylation	[1, 2]

Reference

 [1] Ubiquitin-like protein involved in the proteasome pathway of Mycobacterium tuberculosis.
 Pearce MJ, Mintseris J, Ferreyra J, Gygi SP, Darwin KH.
 Science. 2008 Nov 14;322(5904):1104-7. [PMID: 18832610]
 [2] Prokaryotic ubiquitin-like protein (Pup) proteome of Mycobacterium tuberculosis [corrected] .
 Festa RA, McAllister F, Pearce MJ, Mintseris J, Burns KE, Gygi SP, Darwin KH.
 PLoS One. 2010 Jan 6;5(1):e8589. [PMID: 20066036] 

Functional Description

  

Sequence Annotation

 ACT_SITE 91 91 By similarity.
 ACT_SITE 194 194 By similarity.
 CROSSLNK 173 173 Isoglutamyl lysine isopeptide (Lys-Gln)  

Keyword

 3D-structure; Acyltransferase; Complete proteome; Fatty acid biosynthesis; Fatty acid metabolism; Isopeptide bond; Lipid biosynthesis; Lipid metabolism; Reference proteome; Transferase; Ubl conjugation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 302 AA 

Protein Sequence

Gene Ontology

 GO:0005835; C:fatty acid synthase complex; IDA:MTBBASE.
 GO:0004314; F:[acyl-carrier-protein] S-malonyltransferase activity; IDA:MTBBASE.
 GO:0006633; P:fatty acid biosynthetic process; IDA:MTBBASE.
 GO:0051260; P:protein homooligomerization; IPI:MTBBASE. 

Interpro

 IPR001227; Ac_transferase_dom.
 IPR014043; Acyl_transferase.
 IPR016035; Acyl_Trfase/lysoPLipase.
 IPR016036; Malonyl_transacylase_ACP-bd. 

Pfam

 PF00698; Acyl_transf_1 

SMART

  

PROSITE

  

PRINTS