CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014881
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 UHRF1-binding protein 1 
Protein Synonyms/Alias
 ICBP90-binding protein 1; Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1 
Gene Name
 UHRF1BP1 
Gene Synonyms/Alias
 C6orf107 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
221GRIQIALKRRTKDCNubiquitination[1]
316RLSQYFEKFDVKESSubiquitination[2]
741WQQAQARKLLLASEGubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
 May act as a negative regulator of cell growth. 
Sequence Annotation
 MOD_RES 1106 1106 Phosphoserine.  
Keyword
 Coiled coil; Complete proteome; Phosphoprotein; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1440 AA 
Protein Sequence
MAGIIKKQIL KHLSRFTKNL SPDKINLSTL KGEGQLTNLE LDEEVLQNVL ELPTWLAITR 60
VYCNRASIRI QWTKLKTHPI CLCLDKVEVE MKTCEDPRPP NGQSPIALAS GQSEYGFAEK 120
VVEGMFIIVN SITIKIHSKA FHASFELWQL QGYSVNPNWQ QSDLRLTRIT DPCRGEVLTF 180
KEITWQTLRI EADATDNGDQ DPVTTPLRLI TNQGRIQIAL KRRTKDCNVI SSKLMFLLDD 240
LLWVLTDSQL KAMMKYAESL SEAMEKSAHQ RKSLAPEPVQ ITPPAPSAQQ SWAQAFGGSQ 300
GNSNSSSSRL SQYFEKFDVK ESSYHLLISR LDLHICDDSQ SREPGVSANR LMGGAMQLTF 360
RKMAFDYYPF HWAGDSCKHW VRHCEAMETR GQWAQKLVME FQSKMEKWHE ETGLKPPWHL 420
GVDSLFRRKA DSLSSPRKNP LERSPSQGRQ PAFQPPAWNR LRSSCMVVRV DDLDIHQVST 480
AGQPSKKPST LLSCSRKLHN LPTQVSAIHI EFTEYYFPDN QELPVPCPNL YIQLNGLTFT 540
MDPVSLLWGN LFCLDLYRSL EQFKAIYKLE DSSQKDEHLD IRLDAFWLKV SFPLEKRERA 600
ELHRPQALVF SASGMIATNT RHAPHCSCSD LQSLFRGFAA AEFFHSNYDH FPKVPGGFSL 660
LHMLFLHHAF QMDSCLPQPN TLPPQRPKAS WDLWSVHFTQ ISLDFEGTEN FKGHTLNFVA 720
PFPLSIWACL PLRWQQAQAR KLLLASEGRL KPSASFGSPV QSEALAPDSM SHPRSKTEHD 780
LKSLSGLTEV MEILKEGSSG MDNKGPLTEL EDVADVHMLV HSPAHVRVRL DHYQYLALLR 840
LKEVLQRLQE QLTKDTESMT GSPLQNQTAC IGVLFPSAEV ALLMHPAPGA VDADSAGSDS 900
TSLVDSELSP SEDRELKSDA SSDQGPASPE KVLEESSIEN QDVSQERPHS NGELQDSGPL 960
AQQLAGKGHE AVESLQAKKL SRTQASSSPA ALKPPAGRET AVNGQGELIP LKNIEGELSS 1020
AIHMTKDATK EALHATMDLT KEAVSLTKDA FSLGRDRMTS TMHKMLSLPP AKEPMAKTDE 1080
GVAAPVSGGA ARLRFFSMKR TVSQQSFDGV SLDSSGPEDR ISVDSDGSDS FVMLLESESG 1140
PESVPPGSLS NVSDNAGVQG SPLVNNYGQG SPAANSSVSP SGEDLIFHPV SVLVLKVNEV 1200
SFGIEVRGED LTVALQAEEL TLQQLGTVGL WQFLHGQCPG TCFQESSTLK TGHIRPAVGL 1260
RFEVGPGAAV HSPLASQNGF LHLLLHGCDL ELLTSVLSGL GPFLEDEEIP VVVPMQIELL 1320
NSSITLKDDI PPIYPTSPGP IPITLAMEHV VLKRSDDGVF HIGAAAQDKP SAEVLKSEKR 1380
QPPKEQVFLV PTGEVFEQQV KELPILQKEL IETKQALANA NQDKEKLLQE IRKYNPFFEL 1440 
Gene Ontology
  
Interpro
 IPR026728; UHRF1BP1_like.
 IPR026854; VPS13A_N. 
Pfam
 PF12624; Chorein_N 
SMART
  
PROSITE
  
PRINTS