CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026697
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glutamine--tRNA ligase 
Protein Synonyms/Alias
 Glutaminyl-tRNA synthetase 
Gene Name
 glnS 
Gene Synonyms/Alias
 RPA2905 
Created Date
 July 27, 2013 
Organism
 Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) 
NCBI Taxa ID
 258594 
Lysine Modification
Position
Peptide
Type
References
166LDLFRRMKAGEFPNGacetylation[1]
Reference
 [1] System-wide studies of N-lysine acetylation in Rhodopseudomonas palustris reveal substrate specificity of protein acetyltransferases.
 Crosby HA, Pelletier DA, Hurst GB, Escalante-Semerena JC.
 J Biol Chem. 2012 May 4;287(19):15590-601. [PMID: 22416131] 
Functional Description
  
Sequence Annotation
 MOTIF 38 48 "HIGH" region (By similarity).
 MOTIF 272 276 "KMSKS" region (By similarity).
 BINDING 275 275 ATP (By similarity).  
Keyword
 Aminoacyl-tRNA synthetase; ATP-binding; Complete proteome; Cytoplasm; Ligase; Nucleotide-binding; Protein biosynthesis. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 560 AA 
Protein Sequence
MTTADTAAGE AGRDFIRDIV QADLDSGKHR TIVTRFPPEP NGYLHIGHAK SIALNFGIAQ 60
EFGGRCHLRF DDTNPTKEEQ EYIDSIQADV RWLGFDWGEH MFYASDYFEQ LYAWAELMIK 120
NGDAYVDDQS QDEIRASRGT LTEPGKNSPF RDRSVEENLD LFRRMKAGEF PNGARVLRAK 180
IDMASGNINL RDPVLYRILH AHHPRTGDKW SIYPSYDYAH GQSDAIEGIT HSICTLEFED 240
HRPLYEWLLS KLPVPSQPRQ YEFARLNITY TLLSKRVLTE LVRGGHVAGW DDPRMPTIAG 300
MRRRGVPPAA LRDFVKRIGV AKANSVVDLG MLEFCIREEL NRTAQRRMAV LKPLKVVIEN 360
YPEGQTEELE AINHPDDPSL GTRKIAFGRE IYIEQDDFME NPPKKFFRLS PGNEVRLRYA 420
YFIKCRDVIK NDAGEIVELR CTYDPETRGG NAPDGRKVKA TMHWLPAAQS VKAEIRIYNQ 480
LFANPAPSAS TFADDLNPQS LEVLTEARIE PETAASTSAE PLQFERQGYF VRDRDSTADK 540
PVFNRTIGLR DTFAKEVAKG 560 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005524; F:ATP binding; IEA:HAMAP.
 GO:0004819; F:glutamine-tRNA ligase activity; IEA:HAMAP.
 GO:0006425; P:glutaminyl-tRNA aminoacylation; IEA:InterPro.
 GO:0006424; P:glutamyl-tRNA aminoacylation; IEA:HAMAP. 
Interpro
 IPR001412; aa-tRNA-synth_I_CS.
 IPR004514; Gln-tRNA-synth_Ib.
 IPR022861; Gln_tRNA_ligase_bac.
 IPR000924; Glu/Gln-tRNA-synth_Ib.
 IPR020061; Glu/Gln-tRNA-synth_Ib_a-bdl.
 IPR020058; Glu/Gln-tRNA-synth_Ib_cat-dom.
 IPR020059; Glu/Gln-tRNA-synth_Ib_codon-bd.
 IPR020056; Rbsml_L25/Gln-tRNA_synth_b-brl.
 IPR011035; Ribosomal_L25/Gln-tRNA_synth.
 IPR014729; Rossmann-like_a/b/a_fold. 
Pfam
 PF00749; tRNA-synt_1c
 PF03950; tRNA-synt_1c_C 
SMART
  
PROSITE
 PS00178; AA_TRNA_LIGASE_I 
PRINTS
 PR00987; TRNASYNTHGLU.