| Tag | Content |
|---|
| CPLM ID | CPLM-011143 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | High mobility group protein 1 |
Protein Synonyms/Alias | High spontaneous mutagenesis protein 2 |
Gene Name | HMO1 |
Gene Synonyms/Alias | HSM2; YDR174W; YD9395.07 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 13 | SVKLKSAKDSLVSSL | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | DNA-binding protein that is probably part of the rDNA transcription apparatus. Acts synergetically with the RPA49 subunit of RNA polymerase I during rDNA transcription. May participate in mutagenesis control. |
Sequence Annotation | DNA_BIND 106 179 HMG box. |
Keyword | Complete proteome; Direct protein sequencing; DNA-binding; Nucleus; Reference proteome; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 246 AA |
Protein Sequence | MTTDPSVKLK SAKDSLVSSL FELSKAANQT ASSIVDFYNA IGDDEEEKIE AFTTLTESLQ 60
TLTSGVNHLH GISSELVNPI DDDKDAIIAA PVKAVRRKIE RDPNAPKKPL TVFFAYSAYV 120
RQELREDRQK AGLPPLSSTE ITQEISKKWK ELSDNEKEKW KQAYNVELEN YQREKSKYLE 180
AKKNGTLPPA SLENGPTHAP VPIPFSLQHA AEPPVEKRPH DDDGSSEKKK KKKKKDKKKD 240
KSNSSI 246 |
Gene Ontology | GO:0005829; C:cytosol; IDA:SGD. GO:0005730; C:nucleolus; IDA:SGD. GO:0008301; F:DNA binding, bending; IDA:SGD. GO:0003690; F:double-stranded DNA binding; IDA:SGD. GO:0000400; F:four-way junction DNA binding; IDA:SGD. GO:0060962; P:regulation of ribosomal protein gene transcription from RNA polymerase II promoter; IMP:SGD. GO:0034401; P:regulation of transcription by chromatin organization; IDA:SGD. GO:0006356; P:regulation of transcription from RNA polymerase I promoter; IMP:SGD. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
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