CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026076
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Guanylate binding protein 2 
Protein Synonyms/Alias
 Guanylate nucleotide binding protein 2; Interferon-induced guanylate-binding protein 2 
Gene Name
 Gbp2 
Gene Synonyms/Alias
 rCG_28968 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
374IFLKNSFKDVDQKFQacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 591 AA 
Protein Sequence
MDMASEIHML QPMCLIENTE AHLVINQEAL RILSAINQPV VVVAIVGLYR TGKSYLMNKL 60
AGKRTGFSLG STVQSHTKGI WMWCVPHPKK AGQTLVLLDT EGLEDVEKGD NQNDCWIFAL 120
AVLLSSTFVY NSMGTINQQA MDQLHYVTEL TDLIKSKSSP DQSGIDDSAN FVGFFPTFVW 180
ALRDFSLELE VNGKLVTPDE YLEHSLTLKK GADKKTKSFN EPRLCIRKFF PKRKCFIFDR 240
PALRKQLCKL ETLGEEELCS EFVEQVAEFT SYIFSYSAVK TLSGGIIVNG PRLKSLVQTY 300
VGAISSGSLP CMESAVLTLA QIENSAAVQK AITHYEEQMN QKIQMPTETL QELLDLHRLI 360
EREAIEIFLK NSFKDVDQKF QTELGNLLIS KRDAFIKKNS DVSSAHCSDL IEDIFGPLEE 420
EVKQGTFSKP GGYFLFLQMR QELEKKYNQA PGKGLEAEAV LKKYFESKED IVETLLKTDQ 480
SLTEAAKEIE VERIKAETAE AANRELAEKQ EKFELMMQQK EESYQEHVRQ LTEKMKEEQK 540
KLIEEQDNII ALKLREQEKF LREGYENESK KLLREIENMK RRQSPGKCTI L 591 
Gene Ontology
 GO:0031410; C:cytoplasmic vesicle; IEA:Compara.
 GO:0020005; C:symbiont-containing vacuole membrane; IEA:Compara.
 GO:0005525; F:GTP binding; IEA:InterPro.
 GO:0003924; F:GTPase activity; IEA:InterPro.
 GO:0051856; P:adhesion to symbiont; IEA:Compara.
 GO:0035458; P:cellular response to interferon-beta; IEA:Compara.
 GO:0071346; P:cellular response to interferon-gamma; IEA:Compara.
 GO:0071222; P:cellular response to lipopolysaccharide; IEA:Compara.
 GO:0050830; P:defense response to Gram-positive bacterium; IEA:Compara.
 GO:0042832; P:defense response to protozoan; IEA:Compara.
 GO:0006184; P:GTP catabolic process; IEA:GOC. 
Interpro
 IPR003191; Guanylate-bd_C.
 IPR015894; Guanylate-bd_N.
 IPR027417; P-loop_NTPase. 
Pfam
 PF02263; GBP
 PF02841; GBP_C 
SMART
  
PROSITE
  
PRINTS