CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-004275
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Mitochondrial transcription factor 1 
Protein Synonyms/Alias
 Mitochondrial transcription factor mtTFB; Mitochondrial-specificity factor; RF1023 
Gene Name
 MTF1 
Gene Synonyms/Alias
 YMR228W; YM9959.10 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
84EKRSSLYKFLNAKFEacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 
Functional Description
 Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase. Interacts with DNA in a non-specific manner. 
Sequence Annotation
  
Keyword
 3D-structure; Complete proteome; Direct protein sequencing; DNA-binding; Mitochondrion; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 341 AA 
Protein Sequence
MSVPIPGIKD ISKLKFFYGF KYLWNPTVYN KIFDKLDLTK TYKHPEELKV LDLYPGVGIQ 60
SAIFYNKYCP RQYSLLEKRS SLYKFLNAKF EGSPLQILKR DPYDWSTYSN LIDEERIFVP 120
EVQSSDHIND KFLTVANVTG EGSEGLIMQW LSCIGNKNWL YRFGKVKMLL WMPSTTARKL 180
LARPGMHSRS KCSVVREAFT DTKLIAISDA NELKGFDSQC IEEWDPILFS AAEIWPTKGK 240
PIALVEMDPI DFDFDVDNWD YVTRHLMILK RTPLNTVMDS LGHGGQQYFN SRITDKDLLK 300
KCPIDLTNDE FIYLTKLFME WPFKPDILMD FVDMYQTEHS G 341 
Gene Ontology
 GO:0034245; C:mitochondrial DNA-directed RNA polymerase complex; IDA:SGD.
 GO:0005758; C:mitochondrial intermembrane space; IDA:SGD.
 GO:0005759; C:mitochondrial matrix; IDA:SGD.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0034246; F:mitochondrial RNA polymerase binding promoter specificity activity; IDA:SGD.
 GO:0000179; F:rRNA (adenine-N6,N6-)-dimethyltransferase activity; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0031167; P:rRNA methylation; IEA:GOC. 
Interpro
 IPR016586; Mt_TF_B.
 IPR023165; rRNA_Ade_diMease-like.
 IPR001737; rRNA_Ade_methylase_transferase. 
Pfam
 PF00398; RrnaAD 
SMART
  
PROSITE
 PS01131; RRNA_A_DIMETH 
PRINTS