CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038909
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Inactive phospholipase C-like protein 1 
Protein Synonyms/Alias
 Phospholipase C-like 1 
Gene Name
 Plcl1 
Gene Synonyms/Alias
 rCG_22393 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
868SLSVRMGKKVREYTMacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Transducer. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1096 AA 
Protein Sequence
MAEGAASREA PAPLDVAEGE DDPRAGADAA SGDAAPEASG GRMRDRRSGV ALPGNAGVPA 60
DSEAGLLEAA RATPRRSSII KDPSNQKCGG RKKTVSFSSM PSEKKISSAH DCISFMQAGC 120
ELKKVRPNSR IYNRFFTLDT DLQALRWEPS KKDLEKAKLD ISAIKEIRLG KNTETFRNNG 180
LADQICEDCA FSILHGENYE SLDLVANSAD VANIWVSGLR YLVSRSKQPL DFMEGNQNTP 240
RFMWLKTVFE AADVDGNGIM LEDTSVELIK QLNPTLKESK IRLKFKEIQK SKEKLTTRVT 300
EEEFCEAFCE LCTRPEVYFL LVQISKNKEY LDANDLMLFL EVEQGVTHVT EDMCLDIIRR 360
YELSEDGRQK GFLAIDGFTQ YLLSPECDIF DPEQKKVAQD MTQPLSHYYI NASHNTYLIE 420
DQFRGPADIN GYVRALKMGC RSIELDVSDG PDNEPILCNR NNMAMLLSFR SVLEVINKFA 480
FVASEYPLIL CLGNHCSLPQ QRVMVQQMKK VFGNKLYTEA PLSSESYLPS PEKLKHMIIV 540
KGKKLPSESD LLEGEVTDED EEAEMSRRVS GDYNGEQKHI WLCRELSDLV SICKSVQYRD 600
FELSMKTQNY WEICSFSETL ASRIANEYPE DFVNYNKKFL SRVYPSAMRI DSSNLNPQDF 660
WNCGCQIVAM NFQTPGPMMD LHTGWFLQNG GCGYVLRPSI MRDEVSYFSA NTKGIVPGVS 720
PLLLHIKIIS GQNFPKPKGA CAKGDVIDPY VCVEIHGIPA DCSEQRTKTV QQNSDNPIFD 780
ETFEFQVNLP ELTMVRFVIL DDDYIGDEFI GQYTIPFECL QPGYRHVPLR SFVGDIMEHV 840
TLFVHIAITN RSGGGKAQKR SLSVRMGKKV REYTMLRNIG LKTIDDIFKI AVHPLREAID 900
MRENMQNAIV SVKELCGLPP IASLKQCLLT LSSRLITSDS TPSVSLVMKD CFPYLEPLGT 960
IPDVQKRMLA AYDLMIQESR VLIEMADTVQ EKIVQCQKAG MEFHEELHNL GAKEGLKGRK 1020
LNKAIESFAW NITVLKGQGD LLKNAKNEAV ENIKQIQLAC LSCGLSKGPG SAAEAKGKRS 1080
LEAIEEKESS EENGKL 1096 
Gene Ontology
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:InterPro.
 GO:0005543; F:phospholipid binding; IEA:InterPro.
 GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
 GO:0035556; P:intracellular signal transduction; IEA:InterPro.
 GO:0006629; P:lipid metabolic process; IEA:InterPro. 
Interpro
 IPR000008; C2_Ca-dep.
 IPR008973; C2_Ca/lipid-bd_dom_CaLB.
 IPR018029; C2_membr_targeting.
 IPR011992; EF-hand-like_dom.
 IPR011993; PH_like_dom.
 IPR001192; Pinositol_PLipase_C.
 IPR017946; PLC-like_Pdiesterase_TIM-brl.
 IPR001849; Pleckstrin_homology.
 IPR015359; PLipase_C_EF-hand-like.
 IPR000909; PLipase_C_PInositol-sp_X_dom.
 IPR001711; PLipase_C_Pinositol-sp_Y. 
Pfam
 PF00168; C2
 PF09279; efhand_like
 PF00388; PI-PLC-X
 PF00387; PI-PLC-Y 
SMART
 SM00239; C2
 SM00233; PH
 SM00148; PLCXc
 SM00149; PLCYc 
PROSITE
 PS50004; C2
 PS50003; PH_DOMAIN
 PS50007; PIPLC_X_DOMAIN
 PS50008; PIPLC_Y_DOMAIN 
PRINTS
 PR00390; PHPHLIPASEC.