| Tag | Content |
|---|
| CPLM ID | CPLM-014348 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | StAR-related lipid transfer protein 3 |
Protein Synonyms/Alias | Protein ES 64; Protein MLN 64; START domain-containing protein 3; StARD3 |
Gene Name | Stard3 |
Gene Synonyms/Alias | Es64; Mln64 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 3 | *****MSKRPGDLAC | ubiquitination | [1] | | 282 | IEVPFHGKTFILKTF | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Binds and transports cholesterol. Promotes steroidogenesis in placenta and brain (By similarity). |
Sequence Annotation | DOMAIN 47 218 MENTAL.
DOMAIN 231 444 START.
MOD_RES 210 210 Phosphoserine.
MOD_RES 214 214 Phosphoserine.
MOD_RES 218 218 Phosphoserine.
MOD_RES 222 222 Phosphoserine. |
Keyword | Complete proteome; Endosome; Lipid transport; Lipid-binding; Membrane; Phosphoprotein; Reference proteome; Steroidogenesis; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 446 AA |
Protein Sequence | MSKRPGDLAC DLERSLPALA SLGTSLSHSQ SLSSHFIPPP LEKRRAISDV RRTFCLFVTF 60
DLLFISLLWI IELNTNTGIR KNLEQEVIHY SFQSSFFDIF VLAFFRFSGL LLGYAVLRLQ 120
HWWVIAVTTL VSSAFLIVKV ILSELLSKGA FGYLLPIVSF VLAWLETWFL DFKVLPQEAE 180
EERWYLAAQA AVARGPLLFS GALSEGQFYS PPESFAGSDN ESDEEVTGKK SFSAQEREYI 240
RQGKEATAVV DQILAQEENW KFERSNEYGD TVYTIEVPFH GKTFILKTFL PCPAELVYQE 300
VILQPERMVL WNKTVTACQI LQRVEDNTLV SYDVSSGAAG GVVSPRDFVN VRRIERRRDR 360
YLSSGIATTH CSKPPTHKYV RGENGPGGFI VLKSANNPRV CTFVWILNTD LKGRLPRYLI 420
HQSLGATMFE FAFHLRQRVG ELGARA 446 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005770; C:late endosome; TAS:MGI. GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell. GO:0005739; C:mitochondrion; IDA:MGI. GO:0015485; F:cholesterol binding; IEA:Compara. GO:0017127; F:cholesterol transporter activity; IEA:InterPro. GO:0030301; P:cholesterol transport; IEA:GOC. GO:0006701; P:progesterone biosynthetic process; IMP:MGI. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |