CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033038
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Programmed cell death 10, isoform CRA_b 
Protein Synonyms/Alias
 Programmed cell death protein 10 
Gene Name
 PDCD10 
Gene Synonyms/Alias
 hCG_27561 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
7*MKILEKKSVEVNFTubiquitination[1]
43EFQDLNEKARALKQIubiquitination[2]
69VRFLQTIKDIASAIKubiquitination[3]
87DTVNNVFKKYQYQNRubiquitination[3]
116KSFSDTLKTYFKDGKubiquitination[3]
120DTLKTYFKDGKAINVubiquitination[4, 5]
Reference
 [1] Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin.
 Oshikawa K, Matsumoto M, Oyamada K, Nakayama KI.
 J Proteome Res. 2012 Feb 3;11(2):796-807. [PMID: 22053931]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [5] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 149 AA 
Protein Sequence
MKILEKKSVE VNFTESLLRM AADDVEEYMI ERPEPEFQDL NEKARALKQI LSKIPDEIND 60
RVRFLQTIKD IASAIKELLD TVNNVFKKYQ YQNRRALEHQ KKEFVKYSKS FSDTLKTYFK 120
DGKAINVFVS ANRLIHQTNL ILQTFKTVA 149 
Gene Ontology
  
Interpro
 IPR009652; DUF1241. 
Pfam
 PF06840; DUF1241 
SMART
  
PROSITE
  
PRINTS