CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030730
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein misato homolog 1 
Protein Synonyms/Alias
 cDNA FLJ52644, highly similar to Homo sapiens misato homolog 1 (MSTO1), mRNA 
Gene Name
 MSTO1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
39LGRATDSKEPPGELCubiquitination[1, 2]
73RLILMDLKGSLSSLKubiquitination[1, 2]
80KGSLSSLKEEGGLYRubiquitination[2, 3, 4]
89EGGLYRDKQLDAAIAubiquitination[2, 3, 5]
100AAIAWQGKLTTHKEEubiquitination[4]
105QGKLTTHKEELYPKNubiquitination[2, 3, 4, 5]
140VKSIPNGKGSSPLPTubiquitination[2, 5]
152LPTATTPKPLIPTEAubiquitination[2, 5]
182RSICMIQKYNHDGEAubiquitination[1, 2, 5]
203GQGESVLKEPKYQEEubiquitination[1, 2, 3, 4, 6]
206ESVLKEPKYQEELEDubiquitination[3]
Reference
 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [4] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [5] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [6] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 315 AA 
Protein Sequence
MAGGAREVLT LQLGHFAGFV GAHWWNQQDA ALGRATDSKE PPGELCPDVL YRTGRTLHGQ 60
ETYTPRLILM DLKGSLSSLK EEGGLYRDKQ LDAAIAWQGK LTTHKEELYP KNPYLQDFLS 120
AEGVLSSDGV WRVKSIPNGK GSSPLPTATT PKPLIPTEAS IRVWSDFLRV HLHPRSICMI 180
QKYNHDGEAG RLEAFGQGES VLKEPKYQEE LEDRLHFYVE ECDYLQVVAW QCALQGGSSS 240
HPANYLSSLT PAQGFQILCD LHDGFSGVGA KAAELLQDEY SGRGIITWGL LPGPYHRGVS 300
GTWRSKHSNP IGRVA 315 
Gene Ontology
 GO:0043234; C:protein complex; IEA:InterPro.
 GO:0051258; P:protein polymerization; IEA:InterPro. 
Interpro
 IPR019605; Misato_II_myosin-like.
 IPR003008; Tubulin_FtsZ_GTPase. 
Pfam
 PF10644; Misat_Myo_SegII 
SMART
  
PROSITE
  
PRINTS