CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017675
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 555 
Protein Synonyms/Alias
  
Gene Name
 ZNF555 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
64QQDIYGEKIPKESKIubiquitination[1]
562MRLHTGEKPYQCKHCubiquitination[1, 2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
 May be involved in transcriptional regulation. 
Sequence Annotation
 DOMAIN 4 77 KRAB.
 ZN_FING 172 194 C2H2-type 1; degenerate.
 ZN_FING 200 222 C2H2-type 2.
 ZN_FING 228 250 C2H2-type 3.
 ZN_FING 256 278 C2H2-type 4.
 ZN_FING 284 306 C2H2-type 5.
 ZN_FING 312 334 C2H2-type 6.
 ZN_FING 340 362 C2H2-type 7.
 ZN_FING 368 390 C2H2-type 8.
 ZN_FING 396 418 C2H2-type 9.
 ZN_FING 424 446 C2H2-type 10.
 ZN_FING 452 474 C2H2-type 11.
 ZN_FING 480 502 C2H2-type 12.
 ZN_FING 508 530 C2H2-type 13.
 ZN_FING 536 558 C2H2-type 14.
 ZN_FING 564 586 C2H2-type 15.  
Keyword
 Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 628 AA 
Protein Sequence
MDSVVFEDVA VDFTLEEWAL LDSAQRDLYR DVMLETFQNL ASVDDETQFK ASGSVSQQDI 60
YGEKIPKESK IATFTRNVSW ASVLGKIWDS LSIEDQTTNQ GRNLSRNHGL ERLCESNDQC 120
GEALSQIPHL NLYKKIPPGV KQYEYNTYGK VFMHRRTSLK SPITVHTGHK PYQCQECGQA 180
YSCRSHLRMH VRTHNGERPY VCKLCGKTFP RTSSLNRHVR IHTAEKTYEC KQCGKAFIDF 240
SSLTSHLRSH TGEKPYKCKE CGKAFSYSST FRRHTITHTG EKPYKCKECA EAFSYSSTFR 300
RHMISHTGEK PHKCKECGEA FSYSSAFRRH MITHTGEKPY ECKQCGKTFI YLQSFRRHER 360
IHTGEKPYEC KQCGKTFIYP QSFRRHERTH GGEKPYECNQ CGKAFSHPSS FRGHMRVHTG 420
EKPYECKQCG KTFNWPISLR KHMRTHTREK PYECKQCGKA FSLSACFREH VRMHPEDKSY 480
ECKLCGKAFY CHISLQKHMR RHTAEKLYKC KQCGKAFSWP ELLQQHVRTH TVEKPYECKE 540
CGKVFKWPSS LPIHMRLHTG EKPYQCKHCG KAFNCSSSLR RHVRIHTTEK QYKCNVGHPP 600
ANEFMCSASE KSHQERDLIK VVNMVLPL 628 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS