CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010955
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ARS-binding factor 2, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 ABF2 
Gene Synonyms/Alias
 HIM1; YMR072W; YM9916.11 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
63DHRSQFVKENPTLRPacetylation[1]
75LRPAEISKIAGEKWQacetylation[1]
80ISKIAGEKWQNLEADacetylation[1]
141VFAQHPDKSQLDLMKacetylation[1]
148KSQLDLMKIIGDKWQacetylation[1]
153LMKIIGDKWQSLDQSacetylation[1]
164LDQSIKDKYIQEYKKacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919
Functional Description
 Specific binding to the autonomously replicating sequence 1 (ARS1). Interaction with regulatory regions: probably involved in compacting the mitochondrial genome. It might play a positive role in gene expression and replication. 
Sequence Annotation
 DNA_BIND 43 111 HMG box 1.
 DNA_BIND 116 183 HMG box 2.  
Keyword
 Complete proteome; Direct protein sequencing; DNA-binding; Mitochondrion; Nucleus; Reference proteome; Repeat; Transit peptide. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 183 AA 
Protein Sequence
MNSYSLLTRS FHESSKPLFN LASTLLKASK RTQLRNELIK QGPKRPTSAY FLYLQDHRSQ 60
FVKENPTLRP AEISKIAGEK WQNLEADIKE KYISERKKLY SEYQKAKKEF DEKLPPKKPA 120
GPFIKYANEV RSQVFAQHPD KSQLDLMKII GDKWQSLDQS IKDKYIQEYK KAIQEYNARY 180
PLN 183 
Gene Ontology
 GO:0000262; C:mitochondrial chromosome; IDA:SGD.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0008301; F:DNA binding, bending; IDA:SGD.
 GO:0090139; P:mitochondrial DNA packaging; IMP:SGD.
 GO:0000001; P:mitochondrion inheritance; IMP:SGD. 
Interpro
 IPR009071; HMG_box_dom. 
Pfam
 PF00505; HMG_box 
SMART
 SM00398; HMG 
PROSITE
 PS50118; HMG_BOX_2 
PRINTS