UniProt Accession

 RL28_YEAST; P02406; D6VU43 

Genbank Protein ID

 X01573; Z72625; M19490; BK006941 

Genbank Nucleotide ID

 CAA25729.1; CAA96808.1; AAA35002.1; DAA08004.1 

Protein Name

 60S ribosomal protein L28 

Protein Synonyms/Alias

 L27a; L29; RP44; RP62; YL24 

Gene Name

 RPL28 

Gene Synonyms/Alias

 CYH2; YGL103W 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
47	HHRINMDKYHPGYFG	acetylation	[1]
47	HHRINMDKYHPGYFG	ubiquitination	[2]
55	YHPGYFGKVGMRYFH	acetylation	[1]
63	VGMRYFHKQQAHFWK	acetylation	[1]
70	KQQAHFWKPVLNLDK	acetylation	[1]
70	KQQAHFWKPVLNLDK	ubiquitination	[2]
86	WTLIPEDKRDQYLKS	acetylation	[1]
86	WTLIPEDKRDQYLKS	ubiquitination	[2, 3]
92	DKRDQYLKSASKETA	acetylation	[1]
92	DKRDQYLKSASKETA	ubiquitination	[2]
96	QYLKSASKETAPVID	acetylation	[1]
96	QYLKSASKETAPVID	ubiquitination	[2, 3]
126	PNVPVIVKARFVSKL	ubiquitination	[2, 3]
132	VKARFVSKLAEEKIR	acetylation	[1]
132	VKARFVSKLAEEKIR	ubiquitination	[2, 4]
137	VSKLAEEKIRAAGGV	acetylation	[1]
137	VSKLAEEKIRAAGGV	ubiquitination	[2]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [3] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047]
 [4] A perturbed ubiquitin landscape distinguishes between ubiquitin in trafficking and in proteolysis.
 Ziv I, Matiuhin Y, Kirkpatrick DS, Erpapazoglou Z, Leon S, Pantazopoulou M, Kim W, Gygi SP, Haguenauer-Tsapis R, Reis N, Glickman MH, Kleifeld O.
 Mol Cell Proteomics. 2011 May;10(5):M111.009753. [PMID: 21427232] 

Functional Description

  

Sequence Annotation

 MOTIF 7 13 Nuclear localization signal.
 MOTIF 24 30 Nuclear localization signal.  

Keyword

 3D-structure; Antibiotic resistance; Complete proteome; Cycloheximide resistance; Cytoplasm; Reference proteome; Ribonucleoprotein; Ribosomal protein. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 149 AA 

Protein Sequence

Gene Ontology

 GO:0022625; C:cytosolic large ribosomal subunit; TAS:SGD.
 GO:0005634; C:nucleus; IMP:SGD.
 GO:0003723; F:RNA binding; IDA:SGD.
 GO:0003735; F:structural constituent of ribosome; TAS:SGD.
 GO:0002181; P:cytoplasmic translation; TAS:SGD.
 GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
 GO:0046898; P:response to cycloheximide; IEA:UniProtKB-KW. 

Interpro

 IPR001196; Ribosomal_L15_CS.
 IPR021131; Ribosomal_L18e/L15P. 

Pfam

 PF00828; Ribosomal_L18e 

SMART

  

PROSITE

 PS00475; RIBOSOMAL_L15 

PRINTS