CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001687
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 G patch domain and ankyrin repeat-containing protein 1 
Protein Synonyms/Alias
 Ankyrin repeat domain-containing protein 59; G patch domain-containing protein 10; HLA-B-associated transcript 4; Protein G5 
Gene Name
 GPANK1 
Gene Synonyms/Alias
 ANKRD59; BAT4; G5; GPATCH10 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
261PISSPGFKLLLRGGWubiquitination[1]
290NPIPTVLKRDQEGLGubiquitination[2]
Reference
 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724
Functional Description
  
Sequence Annotation
 REPEAT 111 141 ANK 1.
 REPEAT 142 172 ANK 2.
 DOMAIN 255 301 G-patch.  
Keyword
 ANK repeat; Complete proteome; Polymorphism; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 356 AA 
Protein Sequence
MSRPLLITFT PATDPSDLWK DGQQQPQPEK PESTLDGAAA RAFYEALIGD ESSAPDSQRS 60
QTEPARERKR KKRRIMKAPA AEAVAEGASG RHGQGRSLEA EDKMTHRILR AAQEGDLPEL 120
RRLLEPHEAG GAGGNINARD AFWWTPLMCA ARAGQGAAVS YLLGRGAAWV GVCELSGRDA 180
AQLAEEAGFP EVARMVRESH GETRSPENRS PTPSLQYCEN CDTHFQDSNH RTSTAHLLSL 240
SQGPQPPNLP LGVPISSPGF KLLLRGGWEP GMGLGPRGEG RANPIPTVLK RDQEGLGYRS 300
APQPRVTHFP AWDTRAVAGR ERPPRVATLS WREERRREEK DRAWERDLRT YMNLEF 356 
Gene Ontology
 GO:0003676; F:nucleic acid binding; IEA:InterPro. 
Interpro
 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom.
 IPR000467; G_patch_dom. 
Pfam
 PF12796; Ank_2
 PF01585; G-patch 
SMART
 SM00248; ANK
 SM00443; G_patch 
PROSITE
 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT
 PS50174; G_PATCH 
PRINTS