CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028280
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 EG:BACR25B3.9 protein 
Protein Synonyms/Alias
 Kinesin-like protein at 3A 
Gene Name
 Klp3A 
Gene Synonyms/Alias
 EG:BACR25B3.9; CG8590; Dmel_CG8590 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
612KSKDISAKLAEERRKacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Hydrolase; Microtubule; Motor protein; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1212 AA 
Protein Sequence
MSSEDPSCVA VALRVRPLVQ SELDRGCRIA VERSADGAPQ VTVNRNESYT YNYVFDIDDS 60
QKDLFETCVQ AKVKKLLNGY NVTILAYGQT GSGKTYTMGT AFNGVLDDHV GVIPRAVHDI 120
FTAIAEMQSE FRFAVTCSFV ELYQEQFYDL FSSKTRDKAT VDIREVKNRI IMPGLTELVV 180
TSAQQVTDHL IRGSAGRAVA ATAMNETSSR SHAIFTLTLV ATKLDGKQSV TTSRFNLVDL 240
AGSERCSKTL ASGDRFKEGV NINKGLLALG NVINALGSGQ AAGYIPYRQS KLTRLLQDSL 300
GGNSITLMIA CVSPADYNVA ETLSTLRYAD RALQIKNKPV VNLDPHAAEV NMLKDVIQKL 360
RVELLSGGKM SSSLISAVGA AGLGAIPCEE SLAGSMANAA EIQRLKEQVR TLQDRNRKLQ 420
QELHQSLLDL TEKEMRAHIA EQAHDKLRSH VSELKNKLDQ REQAQFGNEN TNGDNEMRDF 480
SLLVNRVHVE LQRTQEELES QGHESRQRLS SRSHTEGGES GGDEVHEMLH SHSEEYTNKQ 540
MNFAGELRNI NRQLDLKQEL HERIMRNFSR LDSDDEDVKL RLCNQKIDDL EAERRDLMDQ 600
LRNIKSKDIS AKLAEERRKR LQLLEQEISD LRRKLITQAN LLKIRDKERE KIQNLSTEIR 660
TMKESKVKLI RAMRGESEKF RQWKMVREKE LTQLKSKDRK MQSEIVRQQT LHSKQRQVLK 720
RKCEEALAAN KRLKDALERQ ASAQAQRHKY KDNGGSAAGS SNANAKTDSW VDRELEIILS 780
LIDAEHSLEQ LMEDRAVINN HYHLLQQEKT SDPAEAAEQA RILASLEEEL EMRNAQISDL 840
QQKVCPTDLD SRIRSLAEGV QSLGESRTVS KQLLKTLVQQ RRLQASSLNE QRTTLDELRA 900
QLLDAQQQED AASKRLRLLQ SQHEEQMLAQ QRAYEEKVSV LIRTANQRWA EARSPAEDQQ 960
RNQILEELLS SREALQQELD KLRAKNKSKS KAVKSEPQDL DDSFQIVDGN ETVVLSDVSD 1020
DPDWVPSTSK SKRIQSDSRN VISPPEKQDA NVTSLGNSSI QSLNSTSATE DGKRCKGCKC 1080
RTKCTTKRCG CLSGNNACSE TCVCKSNCRN PLNLKDHASQ CGDGDGQKDE TEDADKSDDD 1140
GDDEPQTSKE NAVKFVTPEA PGKVVASPKQ TLQEPKAAAT PLMNSNVVED INGPKLAKMS 1200
GLAFDTPKRK FF 1212 
Gene Ontology
 GO:0005818; C:aster; IDA:FlyBase.
 GO:0005737; C:cytoplasm; IDA:FlyBase.
 GO:0005871; C:kinesin complex; ISS:FlyBase.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0030496; C:midbody; IDA:FlyBase.
 GO:0005634; C:nucleus; IDA:FlyBase.
 GO:0051233; C:spindle midzone; IDA:FlyBase.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0008017; F:microtubule binding; IDA:FlyBase.
 GO:0008574; F:plus-end-directed microtubule motor activity; NAS:FlyBase.
 GO:0000910; P:cytokinesis; IMP:FlyBase.
 GO:0016321; P:female meiosis chromosome segregation; IMP:FlyBase.
 GO:0007140; P:male meiosis; IMP:FlyBase.
 GO:0007018; P:microtubule-based movement; ISS:FlyBase.
 GO:0007067; P:mitosis; IMP:FlyBase.
 GO:0007052; P:mitotic spindle organization; IMP:FlyBase.
 GO:0007344; P:pronuclear fusion; TAS:FlyBase.
 GO:0007131; P:reciprocal meiotic recombination; IMP:FlyBase.
 GO:0007088; P:regulation of mitosis; IMP:FlyBase.
 GO:0051231; P:spindle elongation; IMP:FlyBase. 
Interpro
 IPR019821; Kinesin_motor_CS.
 IPR001752; Kinesin_motor_dom.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00225; Kinesin 
SMART
 SM00129; KISc 
PROSITE
 PS00411; KINESIN_MOTOR_DOMAIN1
 PS50067; KINESIN_MOTOR_DOMAIN2 
PRINTS
 PR00380; KINESINHEAVY.