CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016959
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Trafficking protein particle complex subunit 5 
Protein Synonyms/Alias
  
Gene Name
 TRAPPC5 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
9EARFTRGKSALLERAubiquitination[1, 2, 3, 4]
100VWKALFGKEADKLEQubiquitination[3]
104LFGKEADKLEQANDDubiquitination[5]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [4] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [5] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
 May play a role in vesicular transport from endoplasmic reticulum to Golgi. 
Sequence Annotation
  
Keyword
 Complete proteome; Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus; Polymorphism; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 188 AA 
Protein Sequence
MEARFTRGKS ALLERALARP RTEVSLSAFA LLFSELVQHC QSRVFSVAEL QSRLAALGRQ 60
VGARVLDALV AREKGARRET KVLGALLFVK GAVWKALFGK EADKLEQAND DARTFYIIER 120
EPLINTYISV PKENSTLNCA SFTAGIVEAV LTHSGFPAKV TAHWHKGTTL MIKFEEAVIA 180
RDRALEGR 188 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
 GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
 GO:0030008; C:TRAPP complex; IEA:Compara.
 GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW. 
Interpro
 IPR024096; NO_sig/Golgi_transp_ligand-bd.
 IPR016696; TRAPP-I_Trs31.
 IPR007194; TRAPP_component. 
Pfam
 PF04051; TRAPP 
SMART
  
PROSITE
  
PRINTS