CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017819
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ubiquinone biosynthesis monooxygenase COQ6 
Protein Synonyms/Alias
 Coenzyme Q10 monooxygenase 6 
Gene Name
 Coq6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
86GPKKALEKLSETYSNacetylation[1]
172EAVADRVKVLYESKAacetylation[1]
219LIGADGHKSGVRQAAacetylation[1]
Reference
 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123] 
Functional Description
  
Sequence Annotation
  
Keyword
 Cell projection; Complete proteome; FAD; Flavoprotein; Golgi apparatus; Monooxygenase; Oxidoreductase; Reference proteome; Ubiquinone biosynthesis. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 476 AA 
Protein Sequence
MAARIGSMAG LLCVRWWSSA QLAARGGPLV ASQRWAGSSA DTVYDVVVSG GGLVGSAMAC 60
ALGHDIHFHD KKILLLEAGP KKALEKLSET YSNRVSSISP GSTTLLSSFG AWDHICNMRC 120
KAFRRMQVWD SCSEALIMFD RDNLDDMGYI VENDVIMYAL TKQLEAVADR VKVLYESKAV 180
GYSWPGAFSM ADSSPWVHIT LGDGSTLQTK LLIGADGHKS GVRQAAGIQN VSWKYDQSAV 240
VATLHLSEAT ENNVAWQRFL PSGPIALLPL SDTLSSLVWS TSHEHAAELV SMDEEEFVDA 300
INSAFWSDVH HTDFVDSASA MVRHAVALLK PTKVSARQLP PSIAKVDAKS RALFPLGLGH 360
AAEYVRPRVA LIGDAAHRIH PLAGQGVNMG FGDISSLVHH LSTAAFNGKD LGSMSHLTGY 420
ETDRQRHNTA LLAATDLLKR LYSTSATPLV LLRTWGLQAT NAVSPLKEQI MAFASK 476 
Gene Ontology
 GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.
 GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
 GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; IEA:InterPro.
 GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-UniPathway. 
Interpro
 IPR002938; mOase_FAD-bd.
 IPR003042; Rng_hydrolase-like.
 IPR018168; Ubi_Hdrlase_CS.
 IPR010971; Ubi_Hdrxlases.
 IPR000689; UbQ_biosynth_mOase. 
Pfam
 PF01494; FAD_binding_3 
SMART
  
PROSITE
 PS01304; UBIH 
PRINTS
 PR00420; RNGMNOXGNASE.