| Tag | Content |
|---|
| CPLM ID | CPLM-013482 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | WD repeat-containing protein 81 |
Protein Synonyms/Alias | |
Gene Name | WDR81 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 354 | GSDDNALKQELPRSV | ubiquitination | [1] |
|
Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | |
Sequence Annotation | DOMAIN 337 614 BEACH.
REPEAT 1646 1685 WD 1.
REPEAT 1692 1732 WD 2.
REPEAT 1784 1823 WD 3.
REPEAT 1826 1864 WD 4.
REPEAT 1911 1941 WD 5.
MOD_RES 1136 1136 Phosphoserine (By similarity). |
Keyword | Alternative splicing; Complete proteome; Disease mutation; Mental retardation; Phosphoprotein; Polymorphism; Reference proteome; Repeat; WD repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1941 AA |
Protein Sequence | MDGEPPASSG LGLPDYTSGV SFHDQADLPE TEDFQAGLYV TESPQPQEAE AVSLGRLSDK 60
SSTYQYLPYI SYLVAPGSAS GPSRLNSRKE AGLLAAVTLT QKIIVYLSDT TLMDILPRIS 120
HEVLLPVLSF LTSLVTGFPS GAQARTILCV KTISLIALIC LRIGQEMVQQ HLSEPVATFF 180
QVFSQLHELR QQDLKLDPAG RGEGQLPQVV FSDGQQRPVD PALLDELQKV FTLEMAYTIY 240
VPFSCLLGDI IRKIIPNHEL VGELAALYLE SISPSSRNPA SVEPTMPGTG PEWDPHGGGC 300
PQDDGHSGTF GSVLVGNRIQ IPNDSRPENP GPLGPISGVG GGGLGSGSDD NALKQELPRS 360
VHGLSGNWLA YWQYEIGVSQ QDAHFHFHQI RLQSFPGHSG AVKCVAPLSS EDFFLSGSKD 420
RTVRLWPLYN YGDGTSETAP RLVYTQHRKS VFFVGQLEAP QHVVSCDGAV HVWDPFTGKT 480
LRTVEPLDSR VPLTAVAVMP APHTSITMAS SDSTLRFVDC RKPGLQHEFR LGGGLNPGLV 540
RALAISPSGR SVVAGFSSGF MVLLDTRTGL VLRGWPAHEG DILQIKAVEG SVLVSSSSDH 600
SLTVWKELEQ KPTHHYKSAS DPIHTFDLYG SEVVTGTVSN KIGVCSLLEP PSQATTKLSS 660
ENFRGTLTSL ALLPTKRHLL LGSDNGVIRL LA 692 |
Gene Ontology | GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |