UniProt Accession

 H3BUQ2_HUMAN; H3BUQ2 

Genbank Protein ID

 AC092140 

Genbank Nucleotide ID

  

Protein Name

 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1 

Protein Synonyms/Alias

  

Gene Name

 OGFOD1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
257	ILLKEFLKPEKFTKV	ubiquitination	[1]
263	LKPEKFTKVCEALEH	ubiquitination	[1, 2]
288	PNKRFYEKAEESKLP	ubiquitination	[1, 2]
293	YEKAEESKLPEILKE	ubiquitination	[1]
385	PEENETKKESSVPMC	ubiquitination	[1, 2]
400	QGELRHWKTGHYTLI	ubiquitination	[1]
468	YRDRETLKFVKHINH	ubiquitination	[1, 2, 3]
471	RETLKFVKHINHRSL	ubiquitination	[2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 499 AA 

Protein Sequence

Gene Ontology

 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0031418; F:L-ascorbic acid binding; IEA:InterPro.
 GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro. 

Interpro

 IPR019601; Oxoglutarate/Fe-dep_Oase_C.
 IPR006620; Pro_4_hyd_alph. 

Pfam

 PF10637; Ofd1_CTDD 

SMART

 SM00702; P4Hc 

PROSITE

  

PRINTS