| Tag | Content |
|---|
| CPLM ID | CPLM-017865 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | CD109 antigen |
Protein Synonyms/Alias | GPI-anchored alpha-2 macroglobulin-related protein; CD109 |
Gene Name | Cd109 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 157 | LTLCSDLKPYRTSVD | acetylation | [1] |
|
Reference | [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways. Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y. Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [ PMID: 22826441] |
Functional Description | Modulates negatively TGFB1 signaling in keratinocytes (By similarity). |
Sequence Annotation | REGION 595 704 Bait region (approximate) (By
LIPID 1419 1419 GPI-anchor amidated alanine (Potential).
CARBOHYD 67 67 N-linked (GlcNAc...) (Potential).
CARBOHYD 117 117 N-linked (GlcNAc...) (Potential).
CARBOHYD 246 246 N-linked (GlcNAc...) (Potential).
CARBOHYD 278 278 N-linked (GlcNAc...) (Potential).
CARBOHYD 370 370 N-linked (GlcNAc...) (Potential).
CARBOHYD 421 421 N-linked (GlcNAc...) (Potential).
CARBOHYD 1088 1088 N-linked (GlcNAc...) (Potential).
CROSSLNK 923 926 Isoglutamyl cysteine thioester (Cys-Gln) |
Keyword | Bait region; Cell membrane; Complete proteome; Disulfide bond; Glycoprotein; GPI-anchor; Lipoprotein; Membrane; Protease inhibitor; Reference proteome; Serine protease inhibitor; Signal; Thioester bond. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1442 AA |
Protein Sequence | MRSRRLLSAA HLLCLCAVAL AAPGSRFLVT APGIIRPGAN VTIGVDLLEN SPPQVLVKAQ 60
VFKIASNKSR SILEAEGVFH RGHFKTLVLP ALPLSSADKI YELHINGQSE NEIVFSNRTR 120
LTFESKSISV LIQTDKAFYK PKQEVKFRVL TLCSDLKPYR TSVDIFIKDP KSNVIQQWFS 180
QKGDLGVVSK TFQLSSNPIF GDWSIQVQVN DQQYYQSFQV LEYVLPKFEV TVQTPLYCSL 240
KSKQLNGSVI AKYTYGKPVK GSLSLTFLPL SFWGKKKNIT KSFEINGFAN FSFDNYEMKK 300
VMNLKPLTDV SEGSYENVDP SFPGPAEIIA TVTESLTGIS RMASTNVFFK QHDYIIEIFD 360
YTTVLKPSLN FTATVKVSRS DGNQLTPEEI ENDLVTVVTQ RKNNHPESQR DQEMDYIQTV 420
NYTIPQNGII KIEFPVMSIS GELQLKAYFL DGTSSVTVHS MFTSPSKTYI QLKTRDEYIK 480
VGSPFDLMVS GNRQFKDLSY MVISKGQLVA AGKQSSRTFS LTPEASWAPK ACIIAYYIAE 540
DGEIINDILK IPVQLVFENK VKLFWSKPTV KPSDKVSLRI SATQSDSLVG IVAVDKSVTL 600
MENSNSITME TMVHELELYN TEYYLGMFMN SFAVFQECGL WVLTDATLIR DSIDEVYDTE 660
EYSERFAEEN EANLVDFEDA SSVNNVHVRK NFPETWIWLD AYMGSKIYEE FEVTVPDSIT 720
SWVASAFVIS EDLGFGLTTV PAELQAFQPF FLFLNLPYSV IRGEEFALEV SIVNYLKDTI 780
KVVILIEESD SFDILMTSND TNGTIYRKTV QVPRDNGVTL VFPIKPTHLG EIPITVTAAS 840
PTASDAVTQT IVVKPEGIEK SYSKSVLLDL TDSNVESKQQ SMRFSFPPDT VIGSERVQIT 900
AIGDILGSSI NGLSSLIRMP YGCGEQNMIY FAPNIYILDY LTKQKQLTVN LKEKALSYMR 960
QGYQRELLYQ REDGSFSAFG DIDSSGSTWL SAFVLRCFLE ADYYIDIDQD VLHRTYTWLN 1020
AHKKFNGEFW EPGRVIHSEL QGGTKSPVTL TAYIVTSVLG YKKYQPNIDV QDSIKFLEFE 1080
FSRGISDNYT LAIISYALST VGSPKAEEAL NLLMQRSEKE GDTQFWLSSG PALSGSWQPR 1140
SVDIEIAAYA LLAHTLHHVS EGIPVMRWLI QQRNSLGGFV STQDTVVALK ALSEFSALVH 1200
KENTDIQLTV TGPGIPRSIH FRIDSQNLFL LHQEELHALD PITVNVSAHG SGFAICQLNV 1260
DYNVKGSGSS KRRRSTENQE VFDLDVIVNN EDDISHLNLN VCTSHLGSER TGMVLMEVNL 1320
LSGFSASSDS IPLSETLKKV EYDNGKLNLY LDSVNESQFC VNIPTVRDYK VSNIRDGSVS 1380
VMDYYEPRRQ AVRSYNTQVK LSSCYLSPDT NCKSHTDGAT DSLRRSSSLL VFCSVLLYFV 1440
QH 1442 |
Gene Ontology | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW. GO:0005615; C:extracellular space; IEA:InterPro. GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW. GO:0010951; P:negative regulation of endopeptidase activity; IEA:GOC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |