CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015030
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DNA-directed RNA polymerase subunit beta' 
Protein Synonyms/Alias
 RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta' 
Gene Name
 rpoC 
Gene Synonyms/Alias
 RPA3267 
Created Date
 July 27, 2013 
Organism
 Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) 
NCBI Taxa ID
 258594 
Lysine Modification
Position
Peptide
Type
References
194EAIRELLKGLELEKIacetylation[1]
Reference
 [1] System-wide studies of N-lysine acetylation in Rhodopseudomonas palustris reveal substrate specificity of protein acetyltransferases.
 Crosby HA, Pelletier DA, Hurst GB, Escalante-Semerena JC.
 J Biol Chem. 2012 May 4;287(19):15590-601. [PMID: 22416131
Functional Description
 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; DNA-directed RNA polymerase; Nucleotidyltransferase; Transcription; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1402 AA 
Protein Sequence
MAMNQEIMNL FNPTTPAQVF DQIRISIASP EKILSWSYGE IKKPETINYR TFKPERDGLF 60
CARIFGPIKD YECLCGKYKR MKYKGIICEK CSVEVTLSRV RRERMGHIEL AAPVAHIWFL 120
KSLPSRIGQL LDMTLKDLER ILYFEYYVVL EPGLTDLKER QLLSEEEYLR AQDQYGQDSF 180
TAMIGAEAIR ELLKGLELEK IDAQLRAEMA ETDSDIKHKK LAKRLKIVEA FRYSGNKPEW 240
MILTVVPVIP PDLRPLVPLD GGRFATSDLN DLYRRVINRN NRLKRLMELR APDIIIRNEK 300
RMLQEAVDAL FDNGRRGRVI TGANKRPLKS LADMLKGKQG RFRQNLLGKR VDYSGRSVIV 360
VGPELKLHQC GLPKKMALEL FKPFIYSRLD AKGLSTTVKQ AKKLVEKERP EVWDILDEVI 420
REHPVLLNRA PTLHRLGIQA FEPVLIEGKA IQLHPLVCSA FNADFDGDQM AVHVPLSLEA 480
QLEARVLMMS TNNILHPANG QPIIVPSQDI VLGLYYLSIM REGLPGEGKV FADLAELEHA 540
LYSKVIHLHT KIKYRWHWVN EEGENTVRLL ETTAGRILLG QVLPKSPKLP FDVINKLMTK 600
REISGVIDQV YRHCGQKETV IFCDRIMALG FFNAFKAGIS FGKDDMVVPG SKWKIVDSTR 660
TLAKDFEQQY NDGLITHGEK YNKVVDAWSK ATEEIAKEMM KEISAVRKAP DGSEQQVNSI 720
YMMAHSGARG SPAQMRQLAG MRGLMAKPSG EIIETPIISN FKEGLSVLEY FNSTHGARKG 780
LADTALKTAN SGYLTRRLVD VAQDCIITQA DCGTSLGIKM RAIVDAGTVV ASLGSRILGR 840
TAGEDVRDPA TNEIIVKRGD LMEERDVEAI HQAGVQEVKI RSALTCELVN GICGKCYGRD 900
LARGTPVNHG EAVGVIAAQS IGEPGTQLTM RTFHIGGAAQ INEQSVIESN FDGKIVIKNR 960
AIARNGEGHN VAMVRNMVIA IVDPDGTERA THRIQYGARV HVDEGDMVKR GQRIAEWDPY 1020
TRPILTEVEG EIGFEDLIED QSISETLDES TGIAKRIVID WRSTRGGADL RPAIVIKGKD 1080
GKVLKLARGG DARYMLSVDA ILSVDVGAQV KPGDILARIS TESAKTRDIT GGLPRVAELF 1140
EARRPKDAAI IAEIAGTIRF GRDYKNKRRL SIEPLDKNEE AREYLIPKGK HIHLQDGDVV 1200
EKGDFIVEGN PAPHDILAIK GIEELAAYLV NEIQEVYRLQ GVLINDKHIE VIVRQMLQKI 1260
EITDQGDTDM ISGEQVDKIE FNALNAKAVE EGKKPATGNP VLLGITKASL QTRSFFSAAS 1320
FQETTRVLTE AAVNGKVDPL EGLKENVIVG RLIPAGTGAS MAKIREVAVK RDRLILDERE 1380
KQAAIVPAAA PEAEPLSLPP AE 1402 
Gene Ontology
 GO:0003677; F:DNA binding; IEA:HAMAP.
 GO:0003899; F:DNA-directed RNA polymerase activity; IEA:HAMAP.
 GO:0006351; P:transcription, DNA-dependent; IEA:HAMAP. 
Interpro
 IPR009010; Asp_de-COase-like_dom.
 IPR012754; DNA-dir_RpoC_beta_prime.
 IPR000722; RNA_pol_asu.
 IPR006592; RNA_pol_N.
 IPR007080; RNA_pol_Rpb1_1.
 IPR007066; RNA_pol_Rpb1_3.
 IPR007083; RNA_pol_Rpb1_4.
 IPR007081; RNA_pol_Rpb1_5. 
Pfam
 PF04997; RNA_pol_Rpb1_1
 PF00623; RNA_pol_Rpb1_2
 PF04983; RNA_pol_Rpb1_3
 PF05000; RNA_pol_Rpb1_4
 PF04998; RNA_pol_Rpb1_5 
SMART
 SM00663; RPOLA_N 
PROSITE
  
PRINTS