| Tag | Content |
|---|
| CPLM ID | CPLM-015623 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Inhibitor of nuclear factor kappa-B kinase-interacting protein |
Protein Synonyms/Alias | I kappa-B kinase-interacting protein; IKBKB-interacting protein; IKK-interacting protein |
Gene Name | IKBIP |
Gene Synonyms/Alias | IKIP |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 92 | EFQQLQSKISLISEK | ubiquitination | [1] |
|
Reference | [1] Global identification of modular cullin-RING ligase substrates. Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ. Cell. 2011 Oct 14;147(2):459-74. [ PMID: 21963094] |
Functional Description | Target of p53/TP53 with pro-apoptotic function. |
Sequence Annotation | CARBOHYD 144 144 N-linked (GlcNAc...).
CARBOHYD 328 328 N-linked (GlcNAc...). |
Keyword | Alternative splicing; Coiled coil; Complete proteome; Endoplasmic reticulum; Glycoprotein; Membrane; Phosphoprotein; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 350 AA |
Protein Sequence | MSEVKSRKKS GPKGAPAAEP GKRSEGGKTP VARSSGGGGW ADPRTCLSLL SLGTCLGLAW 60
FVFQQSEKFA KVENQYQLLK LETNEFQQLQ SKISLISEKL ESTESILQEA TSSMSLMTQF 120
EQEVSNLQDI MHDIQNNEEV LTQRMQSLNE KFQNITDFWK RSLEEMNINT DIFKSEAKHI 180
HSQVTVQINS AEQEIKLLTE RLKDLEDSTL RNIRTVKRQE EEDLLRVEEQ LGSDTKAIEK 240
LEEEQHALFA RDEDLTNKLS DYEPKVEECK THLPTIESAI HSVLRVSQDL IETEKKMEDL 300
TMQMFNMEDD MLKAVSEIME MQKTLEGIQY DNSILKMQNE LDILKEKVHD FIAYSSTGEK 360
GTLKEYNIEN KGIGGDF 377 |
Gene Ontology | GO:0005783; C:endoplasmic reticulum; IDA:HGNC. GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0006917; P:induction of apoptosis; IMP:HGNC. GO:0010165; P:response to X-ray; IEP:HGNC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |