CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035707
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Ikzf1 
Protein Synonyms/Alias
 Similar to DNA-binding protein Ikaros form 1-mouse (Predicted), isoform CRA_b 
Gene Name
 Ikzf1 
Gene Synonyms/Alias
 RGD1562979_predicted; rCG_24486 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
192RKSSMPQKFLGDKCLacetylation[1]
338ARNGLALKEEQRAYEacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; DNA-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 428 AA 
Protein Sequence
MDVDEGQDMS QVSGKESPPV SDTPDEGDEP MPVPEDLSTS GAQQNSKSDR GMGERPFQCN 60
QCGASFTQKG NLLRHIKLHS GEKPFKCHLC NYACRRRDAL TGHLRTHSVG KPHKCGYCGR 120
SYKQRSSLEE HKERCHNYLE SMGLPGMYPV IKEETNHSEM AEDLCKIGAE RSLVLDRLAS 180
NVAKRKSSMP QKFLGDKCLS DMPYDSANYE KDEMMTSHVM DQAINNAINY LGAESLRPLV 240
QTPPGSSEVV PVISSMYQLH KPPSDGPPRS NHSAQDSAVE NLLLLSKAKS VSSEREASPS 300
NSCQDSTDTE SNAEEQRSGL IYLTNHITPH ARNGLALKEE QRAYEVLRAA SENSQDAFRV 360
VSTSGEQLKV YKCEHCRVLF LDHVMYTIHM GCHGFRDPFE CNMCGYHSQD RYEFSSHITR 420
GEHRYHLS 428 
Gene Ontology
 GO:0005721; C:centromeric heterochromatin; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0043565; F:sequence-specific DNA binding; IEA:Compara.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Compara.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0030183; P:B cell differentiation; IEA:Compara.
 GO:0030900; P:forebrain development; IEA:Compara.
 GO:0048732; P:gland development; IEA:Compara.
 GO:0048535; P:lymph node development; IEA:Compara.
 GO:0001779; P:natural killer cell differentiation; IEA:Compara.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0048541; P:Peyer's patch development; IEA:Compara.
 GO:0040018; P:positive regulation of multicellular organism growth; IEA:Compara.
 GO:0045660; P:positive regulation of neutrophil differentiation; IEA:Compara.
 GO:0051138; P:positive regulation of NK T cell differentiation; IEA:Compara.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0060041; P:retina development in camera-type eye; IEA:Compara.
 GO:0030217; P:T cell differentiation; IEA:Compara.
 GO:0048538; P:thymus development; IEA:Compara. 
Interpro
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
  
SMART
 SM00355; ZnF_C2H2 
PROSITE
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS