CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042529
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Centromere protein C 1 
Protein Synonyms/Alias
  
Gene Name
 CENPC1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
26QAHEVHQKILATDVSubiquitination[1]
87VIPSSAQKRETYTFEubiquitination[2]
414FSSESKNKLVPEEVTubiquitination[2, 3]
634PKNRIHHKLVLPSNTubiquitination[1]
653RTKRTRLKPLEYWRGubiquitination[1, 2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 728 AA 
Protein Sequence
EASLQFVVEP SEATNRSVQA HEVHQKILAT DVSSKNTPDS KKISSRNIND HHSEADEEFY 60
LSVGSPSVLL DAKTSVSQNV IPSSAQKRET YTFENSVNML PSSTEVSVKT KKRLNFDDKV 120
MLKKIEIDNK VSDEEDKTSE GQERKPSGSS QNRIRDSEYE IQRQAKKSFS TLFLETVKRK 180
SESSPIVRHA ATAPPHSCPP DDTKLIEDEF IIDESDQSFA SRSWITIPRK AGSLKQRTIS 240
PAESTALLQG RKSREKHHNI LPKTLANDKH SHKPHPVETS QPSDKTVLDT SYALIGETVN 300
NYRSTKYEMY SKNAEKPSRS KRTIKQKQRR KFMAKPAEEQ LDVGQSKDEN IHTSHITQDE 360
FQRNSDRNME EHEEMGNDCV SKKQMPPVGS KKSSTRKDKE ESKKKRFSSE SKNKLVPEEV 420
TSTVTKSRRI SRRPSDWWVV KSEESPVYSN SSVRNELPMH HNSSRKSTKK TNQSSKNIRK 480
KTIPLKRQKT ATKGNQRVQK FLNAEGSGGI VGHDEISRCS LSEPLESDEA DLAKKKNLDC 540
SRSTRSSKNE DNIMTAQNVP LKPQTSGYTC NIPTESNLDS GEHKTSVLEE SGPSRLNNNY 600
LMSGKNDVDD EEVHGSSDDS KQSKVIPKNR IHHKLVLPSN TPNVRRTKRT RLKPLEYWRG 660
ERIDYQGRPS GGFVISGVLS PDTISSKRKA KENIGKVNKK SNKKRICLDN DERSMNLFLK 720
VTFRFYFK 728 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005634; C:nucleus; IDA:HPA. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS