UniProt Accession

 B3KY21_HUMAN; B3KY21 

Genbank Protein ID

 AC016888; AK128474; CH471099 

Genbank Nucleotide ID

 BAG54683.1; EAW89189.1 

Protein Name

 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 

Protein Synonyms/Alias

 Solute carrier family 9 (Sodium/hydrogen exchanger), member 3 regulator 1, isoform CRA_a; cDNA FLJ46618 fis, clone TLIVE2007736, highly similar to Ezrin-radixin-moesin-binding phosphoprotein 50 

Gene Name

 SLC9A3R1 

Gene Synonyms/Alias

 hCG_29833 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
195	PQMDWSKKNELFSNL	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 202 AA 

Protein Sequence

Gene Ontology

 GO:0016324; C:apical plasma membrane; IEA:Compara.
 GO:0031526; C:brush border membrane; IEA:Compara.
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0031528; C:microvillus membrane; IEA:Compara.
 GO:0030036; P:actin cytoskeleton organization; IEA:Compara.
 GO:0007191; P:adenylate cyclase-activating dopamine receptor signaling pathway; IEA:Compara.
 GO:0032782; P:bile acid secretion; IEA:Compara.
 GO:0030643; P:cellular phosphate ion homeostasis; IEA:Compara.
 GO:0034613; P:cellular protein localization; IEA:Compara.
 GO:0034635; P:glutathione transport; IEA:Compara.
 GO:0030336; P:negative regulation of cell migration; IEA:Compara.
 GO:0014067; P:negative regulation of phosphatidylinositol 3-kinase cascade; IEA:Compara.
 GO:0010642; P:negative regulation of platelet-derived growth factor receptor signaling pathway; IEA:Compara.
 GO:0051898; P:negative regulation of protein kinase B signaling cascade; IEA:Compara.
 GO:0010766; P:negative regulation of sodium ion transport; IEA:Compara.
 GO:0032416; P:negative regulation of sodium:hydrogen antiporter activity; IEA:Compara.
 GO:0060158; P:phospholipase C-activating dopamine receptor signaling pathway; IEA:Compara.
 GO:0044062; P:regulation of excretion; IEA:Compara.
 GO:0045859; P:regulation of protein kinase activity; IEA:Compara.
 GO:0070293; P:renal absorption; IEA:Compara.
 GO:0003096; P:renal sodium ion transport; IEA:Compara. 

Interpro

 IPR015098; EBP50_C-term.
 IPR001478; PDZ. 

Pfam

 PF09007; EBP50_C-term
 PF00595; PDZ 

SMART

 SM00228; PDZ 

PROSITE

 PS50106; PDZ 

PRINTS