CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027397
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glutaminyl-tRNA synthetase, putative 
Protein Synonyms/Alias
  
Gene Name
 PF13_0170 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Plasmodium falciparum (isolate 3D7) 
NCBI Taxa ID
 36329 
Lysine Modification
Position
Peptide
Type
References
311LNFGLSNKYGGRTHLacetylation[1]
Reference
 [1] Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development.
 Miao J, Lawrence M, Jeffers V, Zhao F, Parker D, Ge Y, Sullivan WJ Jr, Cui L.
 Mol Microbiol. 2013 Aug;89(4):660-75. [PMID: 23796209] 
Functional Description
  
Sequence Annotation
  
Keyword
 Aminoacyl-tRNA synthetase; ATP-binding; Complete proteome; Ligase; Nucleotide-binding; Protein biosynthesis; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 918 AA 
Protein Sequence
MEKIYSKNKL DYLSIIFNFY SWYKRHFKGT LLINENSNIK NTTLIELLGN KKLLLNEINA 60
CEAILKLNEH HENYDSSSGT CNVNNINQPN NNNNNKENIN DNNNNNKENI NDNNNNNKEN 120
NINPCSTNSF NINSFSTNNY NNFNNPCCSF SCNIYDYYDI LKIEELKDFL KDFILRNKKI 180
NKEFFDTIEE DMTMWKKIFF FGQKKRTPEF LDFLLFYILK KENIHFFEEE TRYINLHNWF 240
LKNKIYDISN DKKEDNTPSA CNTNFIQQII EEDLKNKKHT HVITRFPPEP NGYLHLGHAK 300
SICLNFGLSN KYGGRTHLRF DDTNPVTEEI RYIESIKEDV KWLGYDWKEH LYFASNYFEQ 360
LYEWAKILIK QGDAYVDDQS IEEIRKNRGN LKDPGVDSPY RNRTVEENLQ LFENMKNGLY 420
KEGEKVLRAK INMKSGNMNL RDPILYRIMY KIHPKTKNKW VIYPMYDYAH GQSDSIEKIT 480
HSICTLEFET HRPLYEWFQE KLHIFKTRQI EFARLNVTYM VMSKRKLLTL VNEKYVKDWD 540
DPRMPTISGM RRRGYSPDAI KDFCNKVGIA KRENMIPIDL LEFCVREDMD KKAIRLFAIL 600
KPLKVIITNY NDAPDYEHIH NLVASNHPKM EQMGFRNLKF EKEIFIDHDD FQEIPQDNFF 660
RLAPNRTVRL RYAFCITCNE VIKDDQGKVI ELRCTYDPSS KSGLCTNQKK DNVNRQGGDG 720
DNKQGGGGDN KKVKATIHWL CAKNSLQAEF RMYDKLFTKP NPESNEDTEL VQKITSTAHL 780
ENNTNNQGNG KDEYASDTLL QDEHLEDESK NAGWRKYINT NSLIIHKGLV ENYSTRFKIG 840
DPIQFERVGF FTKDKDTTNE LPVFNLTVPL VDNTMLKKKK EDLLQKELDK LKREKIAAER 900
KLKKEQKKIR EQKKKEQN 918 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004819; F:glutamine-tRNA ligase activity; IEA:EC.
 GO:0006425; P:glutaminyl-tRNA aminoacylation; IEA:InterPro. 
Interpro
 IPR001412; aa-tRNA-synth_I_CS.
 IPR004514; Gln-tRNA-synth_Ib.
 IPR000924; Glu/Gln-tRNA-synth_Ib.
 IPR020061; Glu/Gln-tRNA-synth_Ib_a-bdl.
 IPR020058; Glu/Gln-tRNA-synth_Ib_cat-dom.
 IPR020059; Glu/Gln-tRNA-synth_Ib_codon-bd.
 IPR020056; Rbsml_L25/Gln-tRNA_synth_b-brl.
 IPR011035; Ribosomal_L25/Gln-tRNA_synth.
 IPR014729; Rossmann-like_a/b/a_fold. 
Pfam
 PF00749; tRNA-synt_1c
 PF03950; tRNA-synt_1c_C 
SMART
  
PROSITE
 PS00178; AA_TRNA_LIGASE_I 
PRINTS
 PR00987; TRNASYNTHGLU.