UniProt Accession

 ZN738_HUMAN; Q8NE65; A8K4N7 

Genbank Protein ID

 AK291002; AK291193; AC010615; AC022432; BC034499 

Genbank Nucleotide ID

 BAF83691.1; BAF83882.1 

Protein Name

 Protein ZNF738 

Protein Synonyms/Alias

  

Gene Name

 ZNF738 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
12	RYGVYPVKGASGYPG	ubiquitination	[1, 2]
32	LEYSYFEKGPLTFRD	ubiquitination	[1, 2]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

 May be involved in transcriptional regulation. 

Sequence Annotation

 DOMAIN 35 106 KRAB.  

Keyword

 Complete proteome; DNA-binding; Nucleus; Reference proteome; Transcription; Transcription regulation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 137 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
 GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
 GO:0042981; P:regulation of apoptotic process; ISS:UniProtKB.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 

Interpro

 IPR026613; KRAB_dom_C2H2_Znf_fam.
 IPR001909; Krueppel-associated_box. 

Pfam

 PF01352; KRAB 

SMART

 SM00349; KRAB 

PROSITE

 PS50805; KRAB 

PRINTS