CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040773
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Transcription factor Dp-2 
Protein Synonyms/Alias
  
Gene Name
 TFDP2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
252SFGLESGKCSLEDLKubiquitination[1, 2]
259KCSLEDLKLAKSLVPubiquitination[1]
262LEDLKLAKSLVPKALubiquitination[1, 2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; DNA-binding; Nucleus; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 370 AA 
Protein Sequence
MIISTPQRLT SSGSVLIGSP YTPAPAMVTQ THIAEATGWV PGKRSKKGDK NGKGLRHFSM 60
KVCEKVQRKG TTSYNEVADE LVSEFTNSNN HLAADSQAYD QKNIRRRVYD ALNVLMAMNI 120
ISKEKKEIKW IGLPTNSAQE CQNLEIEKQR RIERIKQKRA QLQELLLQQI AFKNLVQRNR 180
QNEQQNQGPP ALNSTIQLPF IIINTSRKTV IDCSISSDKF EYLFNFDNTF EIHDDIEVLK 240
RMGMSFGLES GKCSLEDLKL AKSLVPKALE GYITDISTGP SWLNQGLLLN STQSVSNLDL 300
TTGATLPQSS VNQGLCLDAE VALATGQFLA PNSHQSSSAA SHCSESRGET PCSFNDEDEE 360
DDEEDSSSPE 370 
Gene Ontology
 GO:0005667; C:transcription factor complex; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR003316; E2F_TDP.
 IPR014889; Transc_factor_DP_C.
 IPR016556; Transcription_factor_DP_subgr.
 IPR015648; Transcrpt_fac_DP.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF08781; DP
 PF02319; E2F_TDP 
SMART
  
PROSITE
  
PRINTS