UniProt Accession

 PP14B_HUMAN; Q96C90; Q504S7; Q7KZD7 

Genbank Protein ID

 BT009914; BC014522; BC094817 

Genbank Nucleotide ID

 AAP88916.1; AAH14522.3; AAH94817.1 

Protein Name

 Protein phosphatase 1 regulatory subunit 14B 

Protein Synonyms/Alias

 Phospholipase C-beta-3 neighbouring gene protein 

Gene Name

 PPP1R14B 

Gene Synonyms/Alias

 PLCB3N; PNG 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
114	DARAARVKELLVDCY	ubiquitination	[1]
122	ELLVDCYKPTEAFIS	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 Inhibitor of PPP1CA. Has over 50-fold higher inhibitory activity when phosphorylated (By similarity). 

Sequence Annotation

 MOD_RES 2 2 N-acetylalanine.
 MOD_RES 32 32 Phosphoserine.
 MOD_RES 57 57 Phosphothreonine (By similarity).  

Keyword

 Acetylation; Coiled coil; Complete proteome; Cytoplasm; Phosphoprotein; Protein phosphatase inhibitor; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 147 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
 GO:0042325; P:regulation of phosphorylation; IEA:InterPro. 

Interpro

 IPR008025; PP1_inhibitor. 

Pfam

 PF05361; PP1_inhibitor 

SMART

  

PROSITE

  

PRINTS