CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038978
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Pck2 
Protein Synonyms/Alias
  
Gene Name
 Pck2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
100WLARTDPKDVARVESacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 641 AA 
Protein Sequence
MAAMYLPGLR LSWHRLRPWC RSPCRSIQTL RVLSGDLSQL PAGVRDFVER SAHLCQPAGI 60
HICDGTEAEN AATLALLEEQ GLIRKLPKYE NCWLARTDPK DVARVESKTV IVTSSQRDTV 120
PLLAGGASGQ LGNWMSPDEF QRAVDQRFPG CMQGRTMYVL PFSMGPLGSP LSRIGVQLTD 180
SPYVVASMRI MTRLGTHVLQ ALGDGDFIKC LHSVGQPLTG HGDPVGRWPC NPEKTLIGHV 240
PEQREIVSFG SGYGGNSLLG KKCFALRIAS RLARDEGWLA EHMLILGITN PAGKKRYVAA 300
AFPSACGKTN LAMMREELVA TEAQTFPDTI IKSPSDSPSK ERKLNKESSD FHKHPVATPA 360
PQHNRQEAIV KRKALGSVPS SGGGGETWPI LTDEPMHPGV KFQHHERKVF LPGDKEPCAH 420
PNSRFCVPAR QCPIMDPAWE APEGVPIDAI IFGGRRPKGV PLVYEAFSWR HGVFVGSAMR 480
SESTAAAEHK GKTIMHDPFA MRPFFGYNFG HYLEHWLSME GRKGARLPRI FHVNWFRRDE 540
AGRFLWPGFG ENARVLDWIC RRLGGEDSAR ETPIGLVPKE GALDLSGLRA IDTSQLFSIP 600
KDFWEQEVRD IRSYLTEQVN QDLPKEVLAE LEALEERVQK M 641 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:RGD.
 GO:0005525; F:GTP binding; IEA:InterPro.
 GO:0004613; F:phosphoenolpyruvate carboxykinase (GTP) activity; IDA:RGD.
 GO:0071333; P:cellular response to glucose stimulus; IEP:RGD.
 GO:0006094; P:gluconeogenesis; IDA:RGD.
 GO:0006116; P:NADH oxidation; IDA:RGD.
 GO:0006107; P:oxaloacetate metabolic process; IDA:RGD.
 GO:0032024; P:positive regulation of insulin secretion; IMP:RGD.
 GO:0006090; P:pyruvate metabolic process; IMP:RGD.
 GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD. 
Interpro
 IPR018091; PEP_carboxykin_GTP_CS.
 IPR013035; PEP_carboxykinase_C.
 IPR008209; PEP_carboxykinase_GTP.
 IPR008210; PEP_carboxykinase_N. 
Pfam
 PF00821; PEPCK 
SMART
  
PROSITE
 PS00505; PEPCK_GTP 
PRINTS