CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032005
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Acid phosphatase-like protein 2 
Protein Synonyms/Alias
 cDNA FLJ50551, highly similar to Homo sapiens acid phosphatase-like 2 (ACPL2), mRNA; cDNA, FLJ79020, highly similar to Homo sapiens acid phosphatase-like 2 (ACPL2), mRNA 
Gene Name
 ACPL2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
93LYVIPKTKRPEIDCTubiquitination[1, 2]
172DIYLKKHKLLPNDWSubiquitination[1]
190LYLETTGKSRTLQSGubiquitination[2]
239VRNQYLEKEQRRQYLubiquitination[1]
270KIVDVPTKQLRAANPubiquitination[1, 3]
308MEHFKVIKTHQIEDEubiquitination[1, 2]
427DHHKRSPKPMCPLENubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 463 AA 
Protein Sequence
MDVLTALLLV HLIPVSTPKN GMSSKSRKRI MPDPVTEPPV TDPVYEALLY CNIPSVAERS 60
MEGHAPHHFK LVSVHVFIRH GDRYPLYVIP KTKRPEIDCT LVANRKPYHP KLEAFISHMS 120
KGSGASFESP LNSLPLYPNH PLCEMGELTQ TGVVQHLQNG QLLRDIYLKK HKLLPNDWSA 180
DQLYLETTGK SRTLQSGLAL LYGFLPDFDW KKIYFRHQPS ALFCSGSCYC PVRNQYLEKE 240
QRRQYLLRLK NSQLEKTYGE MAKIVDVPTK QLRAANPIDS MLCHFCHNVS FPCTRNGCVD 300
MEHFKVIKTH QIEDERERRE KKLYFGYSLL GAHPILNQTI GRMQRATEGR KEELFALYSA 360
HDVTLSPVLS ALGLSEARFP RFAARLIFEL WQDREKPSEH SVRILYNGVD VTFHTSFCQD 420
HHKRSPKPMC PLENLVRFVK RDMFVALGGS GTNYYDACHR EGF 463 
Gene Ontology
 GO:0003993; F:acid phosphatase activity; IEA:InterPro. 
Interpro
 IPR000560; His_Pase_superF_clade-2. 
Pfam
 PF00328; His_Phos_2 
SMART
  
PROSITE
  
PRINTS