UniProt Accession

 MLEC_HUMAN; Q14165 

Genbank Protein ID

 D63486; BC000371; BC016297 

Genbank Nucleotide ID

 BAA09773.2; AAH00371.1; AAH16297.1 

Protein Name

 Malectin 

Protein Synonyms/Alias

  

Gene Name

 MLEC 

Gene Synonyms/Alias

 KIAA0152 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
246	YDEGSNLKKQTNKNR	ubiquitination	[1]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

 Carbohydrate-binding protein with a strong ligand preference for Glc2-N-glycan. May play a role in the early steps of protein N-glycosylation (By similarity). 

Sequence Annotation

 BINDING 82 82 Carbohydrate (By similarity).
 BINDING 104 104 Carbohydrate (By similarity).
 BINDING 131 131 Carbohydrate (By similarity).
 BINDING 132 132 Carbohydrate (By similarity).
 BINDING 201 201 Carbohydrate (By similarity).
 CARBOHYD 268 268 N-linked (GlcNAc...) (Potential).  

Keyword

 Carbohydrate metabolism; Complete proteome; Direct protein sequencing; Endoplasmic reticulum; Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 292 AA 

Protein Sequence

Gene Ontology

 GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0030246; F:carbohydrate binding; ISS:UniProtKB.
 GO:0043687; P:post-translational protein modification; TAS:Reactome.
 GO:0006457; P:protein folding; TAS:Reactome.
 GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome. 

Interpro

 IPR021720; Malectin. 

Pfam

 PF11721; Malectin 

SMART

  

PROSITE

  

PRINTS