CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035136
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Fgd3 
Protein Synonyms/Alias
  
Gene Name
 Fgd3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
401VMLYCVPKLRLMGQKacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 676 AA 
Protein Sequence
MELGRSSPTP QEEAISPLGV PDAGLRSSPL GKLQALPFGS GAPQGAQGSS ASAGDSSLGE 60
PSGAMKIPNR DSGIESPSSS VASENFPCEE GSEGSPSPAI LGLHPEVAVD SRAPQDNPQE 120
GEDSGVGEDP DPKITPCRPE EDVGSTQVSR PSSAFNTGHT HIHYTDTHHT HSHTLNQVFC 180
AKLTEAGIPP EVTTGIFSNI SSIYRFHGQF LLPGLKKRIT EEWDTKPRLG DILQKLAPFL 240
KMYGEYVKNF DRAMGLVSTW TQRSPQFKDV IHTIQKQEVC GNLTLQHHML EPVQRVPRYE 300
LLLKDYLKRL PRDAPDRKDA ERSLELISIA ADHSNAAIRK MEKMHKLLEV YEQLGGEEDI 360
VNPANELIKE GNIQKLSAKN GTTQDRHLFL FNNVMLYCVP KLRLMGQKFS VREKMDISDL 420
QVQDVVKPNA ARTFIITGRK RSLELQTRTE EEKKEWIQIE SRKLSSKTRR DKEKPGCKSC 480
GETFNSITKR RYRCKLCGEV ICRKCSEFKA ENSKQSRVCR ECFLEEPLLP TSPSSETPTE 540
LKQNAEKPPS VDPRPSLLCG TLNLSDNGTA WSEVWAAIPE SDPQVLDLLA GSQAGKLLYS 600
IPLSGCNITV PDPEEGLEAG YVWKLHQGSQ TWWLSAPSTK LQQRWLEALS TASRGDTAGD 660
TPGASQPQTP ASTDTP 676 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0005543; F:phospholipid binding; IEA:InterPro.
 GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
 GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. 
Interpro
 IPR000219; DH-domain.
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology.
 IPR000306; Znf_FYVE.
 IPR017455; Znf_FYVE-rel.
 IPR011011; Znf_FYVE_PHD.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
 PF01363; FYVE
 PF00169; PH
 PF00621; RhoGEF 
SMART
 SM00064; FYVE
 SM00233; PH
 SM00325; RhoGEF 
PROSITE
 PS50010; DH_2
 PS50003; PH_DOMAIN
 PS50178; ZF_FYVE 
PRINTS