CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020932
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase 
Protein Synonyms/Alias
 D-xylose 1-dehydrogenase; D-xylose-NADP dehydrogenase; Dimeric dihydrodiol dehydrogenase 
Gene Name
 Dhdh 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
53AQKFNIPKAYGSYEEubiquitination[1]
97GKAVLCEKPMGVNAAacetylation[2]
97GKAVLCEKPMGVNAAubiquitination[1]
251KGMAQIQKLWAPTELubiquitination[1]
332GVTFPQDKR******ubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; NADP; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 333 AA 
Protein Sequence
MALRWGIVSA GLIANDFTTV LSSLPSSEHQ VVAVAARDLN RAEEFAQKFN IPKAYGSYEE 60
LAKDPNVEVA YIATQHPQHK PAVLLCLAAG KAVLCEKPMG VNAAEVREMV AKARSQGVFL 120
MEAIWSRFFP AMEALREVLV QGTIGDLRVA RAEFGFDLSH IPRATDWNQA GGGLLDLGIY 180
CVQFLSMIFG AQKPEKISAV GRIHETGVDD TVSVLLQYPG GVHGSFTCSI SSNLPNTAYV 240
SGTKGMAQIQ KLWAPTELVV NGERKEFPPP VLGKDYNFVN GSCMLYEANH VRECLRKGLK 300
ESPVVPLAES ELLAEILEEA RKAIGVTFPQ DKR 333 
Gene Ontology
 GO:0047837; F:D-xylose 1-dehydrogenase (NADP+) activity; IDA:MGI.
 GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IEA:EC.
 GO:0042843; P:D-xylose catabolic process; IDA:MGI. 
Interpro
 IPR016040; NAD(P)-bd_dom.
 IPR000683; Oxidoreductase_N.
 IPR004104; OxRdtase_C. 
Pfam
 PF01408; GFO_IDH_MocA
 PF02894; GFO_IDH_MocA_C 
SMART
  
PROSITE
  
PRINTS