UniProt Accession

 K7ER15_HUMAN; K7ER15 

Genbank Protein ID

 AC012254; AC051635 

Genbank Nucleotide ID

  

Protein Name

 Haloacid dehalogenase-like hydrolase domain-containing protein 2 

Protein Synonyms/Alias

  

Gene Name

 HDHD2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
182	TVVGKPEKTFFLEAL	ubiquitination	[1, 2]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 204 AA 

Protein Sequence

Gene Ontology

 GO:0016787; F:hydrolase activity; IEA:InterPro. 

Interpro

 IPR023214; HAD-like_dom.
 IPR006357; HAD-SF_hydro_IIA.
 IPR006355; HAD-SF_hydro_IIA_hyp2.
 IPR023215; NPhePase-like_dom. 

Pfam

 PF13344; Hydrolase_6 

SMART

  

PROSITE

  

PRINTS