CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027274
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 1,5-anhydro-D-fructose reductase 
Protein Synonyms/Alias
  
Gene Name
 Akr1e1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
108QLERLLDKPGLRVRPubiquitination[1]
130HPYLNQKKLIDFCHKacetylation[2]
137KLIDFCHKRNVSVTAubiquitination[1]
223EELLSLDKNLRLATFubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 245 AA 
Protein Sequence
MENIPTVGLG TWKLWCTCHK KSLVKTACTN TLEALNLDYL DLYLIHWPMG FKPGEKDIPL 60
DRNGKVIPSH TSFLDTWEAM EDLVFEGLVK NLGVSNFNHE QLERLLDKPG LRVRPITNQI 120
ECHPYLNQKK LIDFCHKRNV SVTAYRPLGG SGGGFHLMDD TVIRKIAKKH GKSPAQILIR 180
FQIQRNLIVI PKSVTPSRIR ENIQVFDFEL TEKDMEELLS LDKNLRLATF PTTENHQDYP 240
FHIEY 245 
Gene Ontology
 GO:0016491; F:oxidoreductase activity; IEA:InterPro. 
Interpro
 IPR001395; Aldo/ket_red.
 IPR018170; Aldo/ket_reductase_CS.
 IPR020471; Aldo/keto_reductase_subgr.
 IPR023210; NADP_OxRdtase_dom. 
Pfam
 PF00248; Aldo_ket_red 
SMART
  
PROSITE
 PS00062; ALDOKETO_REDUCTASE_2
 PS00063; ALDOKETO_REDUCTASE_3 
PRINTS
 PR00069; ALDKETRDTASE.