CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027405
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 26S proteasome regulatory subunit, putative 
Protein Synonyms/Alias
  
Gene Name
 PF13_0033 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Plasmodium falciparum (isolate 3D7) 
NCBI Taxa ID
 36329 
Lysine Modification
Position
Peptide
Type
References
210VVSAIVDKYIGESARacetylation[1]
Reference
 [1] Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development.
 Miao J, Lawrence M, Jeffers V, Zhao F, Parker D, Ge Y, Sullivan WJ Jr, Cui L.
 Mol Microbiol. 2013 Aug;89(4):660-75. [PMID: 23796209] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Nucleotide-binding; Proteasome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 393 AA 
Protein Sequence
MDNKESIKLY VKKVIEHREI ESKVKKLRLD IKELNKKYEK TEDNLKALQS VGQIIGQVLK 60
QLEDEKFIVK ASSGPRYVVG CKSKINKSKL VIGTRVSLDM TTLTVMKRLP CEVDPLVFNM 120
ISDIDKSENS TNKVNYNQIG GLSEQIRQMR EVVELPILNP YLYKRVGIKT PKGVLLYGPP 180
GTGKTLLARA MASNINCNFM RIVVSAIVDK YIGESARIIR EMFNYAKEHQ PCIIFMDEID 240
AIGGRRFSQG TSADREIQRT LMELLNHLDG FEELGNVKII MATNRPDVLD PALVRPGRLD 300
RKIEIPLPNE TARIEILKIH ANKMTKLGDI DYESVCRLCD GFNGADLRNV CTEAGMFAIR 360
AMRDYVIEED FYKAARKISE GKKLEGKIEY EKI 393 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0005838; C:proteasome regulatory particle; ISS:GeneDB_Pfalciparum.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004175; F:endopeptidase activity; ISS:GeneDB_Pfalciparum.
 GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
 GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:GeneDB_Pfalciparum. 
Interpro
 IPR005937; 26S_Psome_P45.
 IPR003593; AAA+_ATPase.
 IPR003959; ATPase_AAA_core.
 IPR003960; ATPase_AAA_CS.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00004; AAA 
SMART
 SM00382; AAA 
PROSITE
 PS00674; AAA 
PRINTS